Meningococcal meningitis outbreak control strategies.

dc.contributor.authorAhlawat, Sen_US
dc.contributor.authorKumar, Ren_US
dc.contributor.authorRoy, Pen_US
dc.contributor.authorVarma, Sen_US
dc.contributor.authorSharma, B Ken_US
dc.date.accessioned2000-12-24en_US
dc.date.accessioned2009-06-01T18:17:18Z
dc.date.available2000-12-24en_US
dc.date.available2009-06-01T18:17:18Z
dc.date.issued2000-12-24en_US
dc.description49 references.en_US
dc.description.abstractMeningococcal meningitis has been occurring worldwide in both endemic and epidemic forms. Serogroup A accounts for majority of cases of epidemic as well as endemic Meningococcal meningitis in developing nations, whereas group C and group B causes epidemic and endemic meningococcal meningitis in developed countries. Person to person spread of N. meningitides generally occurs through inhalation of droplets of infected nasopharyngeal secretions by direct or indirect oral contact. Incubation period varies from 2 to 10 days. N. meningitides typically causes acute infective illness characterized by sequential development of upper respiratory tract infection, meningococcemia, meningitis and focal neurological deficit. Over 90 per cent cases of adult meningococcal infections have cerebrospinal meningitis, whereas in children prevalence of meningitis is much lower (50 per cent). Acute meningitis manifests with fever, severe headache, vomiting and neck stiffness. Presentations may be non-specific in infants, elderly and in patients with fulminant meningococcemia. Diagnosis is confirmed with cerebrospinal fluid analysis. Overall mortality due to meningitis is usually around 10 per cent. In meningococcal septicemia, the case fatality rate may exceed 50 per cent. Preventive strategies include vaccination, chemoprophylaxis and early detection and treatment. Mass vaccination campaign, if appropriately carried out, has been documented to halt an epidemic of meningococcal disease due to serogroup A or C. In the present review we have discussed the available evidence with regards to prevention at primary, secondary and tertiary level. Public health approach to an outbreak of meningococcal meningitis in a community or an organization is also outlined.en_US
dc.description.affiliationDept. of Community Medicine, Postgraduate Institute of Medical Education & Research, Chandigarh-160012.en_US
dc.identifier.citationAhlawat S, Kumar R, Roy P, Varma S, Sharma BK. Meningococcal meningitis outbreak control strategies. Journal of Communicable Diseases. 2000 Dec; 32(4): 264-74en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/112115
dc.language.isoengen_US
dc.subject.meshDisease Outbreaks --prevention & controlen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshIndia --epidemiologyen_US
dc.subject.meshMaleen_US
dc.subject.meshMeningitis, Meningococcal --diagnosisen_US
dc.subject.meshMeningococcal Vaccinesen_US
dc.subject.meshPrimary Preventionen_US
dc.subject.meshPublic Healthen_US
dc.titleMeningococcal meningitis outbreak control strategies.en_US
dc.typeJournal Articleen_US
dc.typeReviewen_US
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