Association of micro and macrovascular complications with fatty liver in patients with type 2 diabetes mellitus.
Loading...
Date
2014-01
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Background:Fatty liver is a fairly common entity seen in the diabetic population.
Studies showed that liver adiposity is independently associated with Insulin Resistance
and can substantially increase the risk of various micro and macrovascular
complications of diabetes mellitus.
Aims: Identifying various micro and macrovascular complications and finding their
association with fatty liver disease in type 2 diabetes patients.
Material and methods: 141 diabetic patients admitted in a tertiary care center over a
two year period were screened for fatty liver by ultrasonography of the abdomen and
were classified into FL (fatty Liver) group and NFL (non fatty liver) group. All patients
were investigated for complications like nephropathy, neuropathy, retinopathy,
cardiac and peripheral vascular disease. Statistical analysis was done to find the
association of complications with fatty liver.
Results: out of 141 patients, 49 (35%) had fatty liver. Leading complication was
neuropathy (31.2%), followed by nephropathy (11.3 %), retinopathy (10.6 %), cardiac
disease (9.2%) and peripheral vascular disease (3.55). Between FL and NFL groups,
Diabetic neuropathy (40.8% vs 23.9%) and cardiac disease (16.3% vs 5.4%) showed
statical significance (p<0.05), while other complications were more or less equally
prevalent in the two groups.
Conclusions: Fatty liver is seen in one third of diabetic patients. vascular complications
like neuropathy and cardiac disease are more commonly seen in diabetic patients with
fatty liver than those without fatty liver.
Description
Keywords
Fatty liver, Diabetes, vascular complications
Citation
Suresh V, Guptha NSRC, Bhargavi EU. Association of micro and macrovascular complications with fatty liver in patients with type 2 diabetes mellitus. International Journal of Medical and Dental Sciences. 2014 Jan; 3(1): 270-275.