Angiotensin-1 converting enzyme I/D gene polymorphism: scenario in Malaysia.

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dc.contributor.authorJayapalan, J Jen_US
dc.contributor.authorMuniandy, Sen_US
dc.contributor.authorChan, S Pen_US
dc.date.accessioned2009-05-27T16:10:42Z
dc.date.available2009-05-27T16:10:42Z
dc.date.issued2008-09-09en_US
dc.descriptionThe Southeast Asian Journal of Tropical Medicine and Public Health.en_US
dc.description.abstractDiscrepancies in angiotensin-1 converting enzyme (ACE) allele genetic susceptibility with disease etiology have been attributed to ethnic differences. We investigated ACE gene polymorphism of the multiethnic Malaysian population by utilizing nested polymerase chain reaction. Allelic frequency of 0.65 and 0.35 for I and D allele, respectively in the pooled population was comparable with other Asian populations. A significant association was found between the Malaysian ethnic groups and ACE I/D genotype. The II genotype was found at higher frequency among the Malays but a greater frequency of DD genotype among Indians.en_US
dc.description.affiliationDepartment of Molecular Medicine, University of Malaya, Kuala Lumpur, Malaysia.en_US
dc.identifier.citationJayapalan JJ, Muniandy S, Chan SP. Angiotensin-1 converting enzyme I/D gene polymorphism: scenario in Malaysia. The Southeast Asian Journal of Tropical Medicine and Public Health. 2008 Sep; 39(5): 917-21en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/34601
dc.language.isoengen_US
dc.source.urihttps://www.tm.mahidol.ac.th/seameo/2008_39_5/23-4318.pdfen_US
dc.subject.meshContinental Population Groupsen_US
dc.subject.meshGene Frequencyen_US
dc.subject.meshGenetics, Populationen_US
dc.subject.meshGenotypeen_US
dc.subject.meshHumansen_US
dc.subject.meshMalaysiaen_US
dc.subject.meshPeptidyl-Dipeptidase A --geneticsen_US
dc.subject.meshPolymerase Chain Reactionen_US
dc.subject.meshPolymorphism, Geneticen_US
dc.titleAngiotensin-1 converting enzyme I/D gene polymorphism: scenario in Malaysia.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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