Efficacy and safety of Tinospora cordifolia (Tc) as an add-on therapy in patients with type-2 diabetes.
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Date
2015-05
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Abstract
Background: Type 2 diabetes has become a global epidemic. Tinospora cordifolia is being used in the treatment of type 2 diabetes since ancient times. It is a common misconception that Ayurvedic medicines are always safe. In fact, they also pose serious health risks either in the form of adverse reactions or in the form of drug interactions. Hence this study was undertaken to study the efficacy and safety of Tc on human subjects.
Methods: We recruited 40 type 2 diabetic patients who were on oral hypoglycaemic agents. These patients were then randomly divided into two groups, A and B. Patients in group A continued with their anti-diabetic medications while in group B Tc was given at a dose of 500 mg three times daily along with their conventional medications. The fasting and post prandial blood glucose levels, renal function tests and liver function tests were recorded at baseline, 3 months and 6 months.
Results: During the course of study we observed a decrease in the fasting and post prandial blood glucose levels of the patients. No significant change was observed in the renal function tests and liver function tests and no other event of any adverse drug reactions were recorded.
Conclusion: Tinospora cordifolia (Tc) is effective as an add-on therapy in patients with type-2 diabetes. There is no negative impact of Tc on the renal as well as liver function tests.
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Keywords
Type 2 diabetes, Tinospora cordifolia, Oral hypoglycaemic agents
Citation
Mishra Saumya, Verma Narsingh, Bhattacharya Sandeep, Usman Kauser, Reddy Himanshu, Verma Neera, Anjum Baby, Singh Prerna, Bharadwaj Shipra, Bharadwaj Kshitij. Efficacy and safety of Tinospora cordifolia (Tc) as an add-on therapy in patients with type-2 diabetes. International Journal of Research in Medical Sciences. 2015 May; 3(5): 1109-1113.