Drug-resistant tuberculosis among prisoners of three prisons in Bangkok and the vicinity.

dc.contributor.authorTansuphasiri, Unchaleeen_US
dc.contributor.authorPleumpanupat, Wannapenen_US
dc.contributor.authorPandii, Wongdyanen_US
dc.contributor.authorRienthong, Somsaken_US
dc.date.accessioned2009-05-27T21:54:34Z
dc.date.available2009-05-27T21:54:34Z
dc.date.issued2003-10-03en_US
dc.descriptionChotmaihet Thangphaet.en_US
dc.description.abstractThe purpose of this study was to determine the prevalence of drug-resistant tuberculosis and some factors associated with drug resistance among prisoners of three prisons in Bangkok and the vicinity. Susceptibility testing to four first-line antituberculous drugs was performed on 165 M. tuberculosis strains isolated from prisoners of three prisons including Klongprem Central (KC) prison, Bangkwang Central (BC) prison and the Correctional Institution (CI) for Male Drug Addicts. Of 165 smear positive tuberculosis (TB) cases with drugs susceptibility results, resistance to one or more drugs was 49.7 per cent. Resistance to one, two, three, and four drugs was 20.0, 13.3, 4.2 and 12.1 per cent, respectively. Multidrug resistant tuberculosis (MDR-TB) was 18.8 per cent. Patients classified as primary and acquired drug resistant were 6.7 and 50.0 per cent. The primary drug resistance to one or more drugs among prisoners at KC, BC and CI were 42.5, 36.4 and 53.9 per cent, respectively and MDR-TB were 8.2, 3.0, and 7.7 per cent, respectively. Of several factors analyzed in the present study, only a history of previous TB treatment was significantly associated with drug resistance (p < 0.05). In conclusion, the results indicate the high prevalence of drug-resistant tuberculosis and the seriousness of the TB problem in prisons. The public health sector and prison authorities should work in close collaboration and co-ordination to continue improving TB case detection. Directly Observed Treatment Short course (DOTS) is highly recommended. Moreover, discharged prisoners with tuberculosis should be appropriately referred to hospitals or TB control centers.en_US
dc.description.affiliationDepartment of Microbiology, Faculty of Public Health, Mahidol University, Bangkok 10400, Thailand.en_US
dc.identifier.citationTansuphasiri U, Pleumpanupat W, Pandii W, Rienthong S. Drug-resistant tuberculosis among prisoners of three prisons in Bangkok and the vicinity. Journal of the Medical Association of Thailand. 2003 Oct; 86(10): 953-63en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/45614
dc.language.isoengen_US
dc.source.urihttps://www.mat.or.th/journal/all.phpen_US
dc.subject.meshAdulten_US
dc.subject.meshDrug Resistance, Multiple, Bacterial --physiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMycobacterium tuberculosis --physiologyen_US
dc.subject.meshPrevalenceen_US
dc.subject.meshPrisonersen_US
dc.subject.meshSubstance-Related Disordersen_US
dc.subject.meshThailand --epidemiologyen_US
dc.subject.meshTuberculosis, Pulmonary --epidemiologyen_US
dc.titleDrug-resistant tuberculosis among prisoners of three prisons in Bangkok and the vicinity.en_US
dc.typeJournal Articleen_US
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