Saccharomyces boulardii: An Efficient Yeast Probiotic for Pediatric Gut Dysbiosis Management

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dc.contributor.authorReddy, ADen_US
dc.contributor.authorParija, Aen_US
dc.contributor.authorMadhavi, Ben_US
dc.contributor.authorMadhav, SVen_US
dc.contributor.authorShalini, Ben_US
dc.contributor.authorSreenivasulu, Men_US
dc.contributor.authorVenkatswami, Pen_US
dc.contributor.authorReddy, TRKen_US
dc.contributor.authorGopal, SH.en_US
dc.date.accessioned2025-05-12T08:15:09Z
dc.date.available2025-05-12T08:15:09Z
dc.date.issued2024-08
dc.description.abstractThe human microbiome, comprising diverse microorganisms across body surfaces, profoundly influences host physiology, metabolism, and nutrition. Dysbiosis, an imbalance within gut microbiota, triggers health issues such as inflammation, autoimmune disorders, and obesity. Probiotics, which are live microorganisms known for their health benefits, when used correctly, hold promise for managing dysbiosis. Prebiotics, probiotics, synbiotics, and immunobiotics have demonstrated efficacy in addressing gut dysbiosis. Among these supplements, yeast-based probiotics such as Saccharomyces boulardii CNCM I-745 demonstrate significant benefits over bacterial alternatives. Yeast cells, being larger and more resistant to digestive enzymes and bile than bacterial cells, serve as a barrier against pathogens and possess immunomodulatory properties, enhancing gut health. S. boulardii CNCM I-745, with its unique features such as pathogen binding, immune stimulation, and toxin neutralization without genetic transfer, notably mitigates antibiotic resistance risk. It effectively prevents antibiotic-associated diarrhea and pediatric acute gastroenteritis compared to bacterial probiotics, endorsed by the international guidelines for managing acute diarrhea safely. In addition, oral probiotics may aid microbiota restoration and potentially prevent other diseases.en_US
dc.identifier.affiliationsDheeraj Hospital, Proddatur, Andhra Pradesh, India, Sai Sudha Clinic, Cuttack, Odisha, India, Mathrutva Children’s and Speciality Clinic, Tirupati, Andhra Pradesh, India, Om Clinic, Hanamkonda, Telangana, India, Shalini Childrens Clinic, Hyderabad, Telangana, India, Hrudaya Hospital, Anantapur, Andhra Pradesh, India, PVS Hospital, Nellore, Andhra Pradesh, India, Department of General Surgeon, Sri Sai Suraksha Children’s Hospital, Kurnool, Andhra Pradesh, India, Dr. S Harigopal Clinic, Rajampet, Andhra Pradesh, Indiaen_US
dc.identifier.affiliationsDheeraj Hospital, Proddatur, Andhra Pradesh, India, Sai Sudha Clinic, Cuttack, Odisha, India, Mathrutva Children’s and Speciality Clinic, Tirupati, Andhra Pradesh, India, Om Clinic, Hanamkonda, Telangana, India, Shalini Childrens Clinic, Hyderabad, Telangana, India, Hrudaya Hospital, Anantapur, Andhra Pradesh, India, PVS Hospital, Nellore, Andhra Pradesh, India, Department of General Surgeon, Sri Sai Suraksha Children’s Hospital, Kurnool, Andhra Pradesh, India, Dr. S Harigopal Clinic, Rajampet, Andhra Pradesh, Indiaen_US
dc.identifier.affiliationsDheeraj Hospital, Proddatur, Andhra Pradesh, India, Sai Sudha Clinic, Cuttack, Odisha, India, Mathrutva Children’s and Speciality Clinic, Tirupati, Andhra Pradesh, India, Om Clinic, Hanamkonda, Telangana, India, Shalini Childrens Clinic, Hyderabad, Telangana, India, Hrudaya Hospital, Anantapur, Andhra Pradesh, India, PVS Hospital, Nellore, Andhra Pradesh, India, Department of General Surgeon, Sri Sai Suraksha Children’s Hospital, Kurnool, Andhra Pradesh, India, Dr. S Harigopal Clinic, Rajampet, Andhra Pradesh, Indiaen_US
dc.identifier.affiliationsDheeraj Hospital, Proddatur, Andhra Pradesh, India, Sai Sudha Clinic, Cuttack, Odisha, India, Mathrutva Children’s and Speciality Clinic, Tirupati, Andhra Pradesh, India, Om Clinic, Hanamkonda, Telangana, India, Shalini Childrens Clinic, Hyderabad, Telangana, India, Hrudaya Hospital, Anantapur, Andhra Pradesh, India, PVS Hospital, Nellore, Andhra Pradesh, India, Department of General Surgeon, Sri Sai Suraksha Children’s Hospital, Kurnool, Andhra Pradesh, India, Dr. S Harigopal Clinic, Rajampet, Andhra Pradesh, Indiaen_US
dc.identifier.affiliationsDheeraj Hospital, Proddatur, Andhra Pradesh, India, Sai Sudha Clinic, Cuttack, Odisha, India, Mathrutva Children’s and Speciality Clinic, Tirupati, Andhra Pradesh, India, Om Clinic, Hanamkonda, Telangana, India, Shalini Childrens Clinic, Hyderabad, Telangana, India, Hrudaya Hospital, Anantapur, Andhra Pradesh, India, PVS Hospital, Nellore, Andhra Pradesh, India, Department of General Surgeon, Sri Sai Suraksha Children’s Hospital, Kurnool, Andhra Pradesh, India, Dr. S Harigopal Clinic, Rajampet, Andhra Pradesh, Indiaen_US
dc.identifier.affiliationsDheeraj Hospital, Proddatur, Andhra Pradesh, India, Sai Sudha Clinic, Cuttack, Odisha, India, Mathrutva Children’s and Speciality Clinic, Tirupati, Andhra Pradesh, India, Om Clinic, Hanamkonda, Telangana, India, Shalini Childrens Clinic, Hyderabad, Telangana, India, Hrudaya Hospital, Anantapur, Andhra Pradesh, India, PVS Hospital, Nellore, Andhra Pradesh, India, Department of General Surgeon, Sri Sai Suraksha Children’s Hospital, Kurnool, Andhra Pradesh, India, Dr. S Harigopal Clinic, Rajampet, Andhra Pradesh, Indiaen_US
dc.identifier.affiliationsDheeraj Hospital, Proddatur, Andhra Pradesh, India, Sai Sudha Clinic, Cuttack, Odisha, India, Mathrutva Children’s and Speciality Clinic, Tirupati, Andhra Pradesh, India, Om Clinic, Hanamkonda, Telangana, India, Shalini Childrens Clinic, Hyderabad, Telangana, India, Hrudaya Hospital, Anantapur, Andhra Pradesh, India, PVS Hospital, Nellore, Andhra Pradesh, India, Department of General Surgeon, Sri Sai Suraksha Children’s Hospital, Kurnool, Andhra Pradesh, India, Dr. S Harigopal Clinic, Rajampet, Andhra Pradesh, Indiaen_US
dc.identifier.affiliationsDheeraj Hospital, Proddatur, Andhra Pradesh, India, Sai Sudha Clinic, Cuttack, Odisha, India, Mathrutva Children’s and Speciality Clinic, Tirupati, Andhra Pradesh, India, Om Clinic, Hanamkonda, Telangana, India, Shalini Childrens Clinic, Hyderabad, Telangana, India, Hrudaya Hospital, Anantapur, Andhra Pradesh, India, PVS Hospital, Nellore, Andhra Pradesh, India, Department of General Surgeon, Sri Sai Suraksha Children’s Hospital, Kurnool, Andhra Pradesh, India, Dr. S Harigopal Clinic, Rajampet, Andhra Pradesh, Indiaen_US
dc.identifier.affiliationsDheeraj Hospital, Proddatur, Andhra Pradesh, India, Sai Sudha Clinic, Cuttack, Odisha, India, Mathrutva Children’s and Speciality Clinic, Tirupati, Andhra Pradesh, India, Om Clinic, Hanamkonda, Telangana, India, Shalini Childrens Clinic, Hyderabad, Telangana, India, Hrudaya Hospital, Anantapur, Andhra Pradesh, India, PVS Hospital, Nellore, Andhra Pradesh, India, Department of General Surgeon, Sri Sai Suraksha Children’s Hospital, Kurnool, Andhra Pradesh, India, Dr. S Harigopal Clinic, Rajampet, Andhra Pradesh, Indiaen_US
dc.identifier.citationReddy AD, Parija A, Madhavi B, Madhav SV, Shalini B, Sreenivasulu M, Venkatswami P, Reddy TRK, Gopal SH.. Saccharomyces boulardii: An Efficient Yeast Probiotic for Pediatric Gut Dysbiosis Management. International Journal of Scientific Study. 2024 Aug; 12(5): 17-27en_US
dc.identifier.issn2321-6379
dc.identifier.issn2321-595X
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/246967
dc.languageenen_US
dc.publisherInternational Research Organization for Life & Health Sciencesen_US
dc.relation.issuenumber5en_US
dc.relation.volume12en_US
dc.source.urihttps://www.ijss-sn.com/uploads/2/0/1/5/20153321/ijss_aug_24_ra02_-_2024.pdfen_US
dc.subjectDysbiosisen_US
dc.subjectGut healthen_US
dc.subjectMicrobiomeen_US
dc.subjectProbioticsen_US
dc.subjectSaccharomyces boulardii CNCM I-745en_US
dc.titleSaccharomyces boulardii: An Efficient Yeast Probiotic for Pediatric Gut Dysbiosis Managementen_US
dc.typeJournal Articleen_US
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