Connective tissue stromal changes in tumours and tumour-like lesions of the breast.
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1999-07-22
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Abstract
Between June 1994 and December 1995, one hundred and fifteen tumours and tumour-like lesions of the breast were studied in the Department of Pathology, Kasturba Medical College, Mangalore. Neoplasms constituted 80.9% and tumour like lesions accounted for 19.13%. Among the tumours, 51.6% were benign and 48.4% were malignant. Tumour-like lesions included the entire spectrum of fibrocystic disease. Tumours were common between 2nd and 8th decades while tumour-like lesions were uncommon above 6th decade. Whereas benign tumours exhibited ground substance, collagen and reticulin fibres in varying amounts, tumour-like lesions and carcinoma showed more of collagen fibres and less of ground substance. Elastosis and lymphoplasmacytic infiltrate were prominent features in carcinomas rather than in benign lesions.
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Pai MR, Pai KN, Rao RV, Naik R, Shankarnarayana , Baliga P. Connective tissue stromal changes in tumours and tumour-like lesions of the breast. Indian Journal of Pathology & Microbiology. 1999 Jul; 42(3): 327-32