Pulmonary involvement predicts mortality in severe leptospirosis patients.

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dc.contributor.authorBudiono, Ekoen_US
dc.contributor.authorSumardi,en_US
dc.contributor.authorRiyanto, Bambang Sigiten_US
dc.contributor.authorHisyam, Barmawien_US
dc.contributor.authorHartopo, Anggoro Budien_US
dc.date.accessioned2009-01-05en_US
dc.date.accessioned2009-05-28T04:36:47Z
dc.date.available2009-01-05en_US
dc.date.available2009-05-28T04:36:47Z
dc.date.issued2009-01-05en_US
dc.description.abstractAim: to evaluate the influence of pulmonary involvement at admission in predicting mortality among patients with severe leptospirosis. Methods: reprospective cohort study from medical record registry in Dr. Sardjito Hospital, Yogyakarta from 2003 to 2007. Pulmonary involvement was defined by the presence of pulmonary infiltrate, consolidation or pleural effusion in thorax radiography. Pulmonary edema was excluded. Admission data were collected. Follow-up records were noted until patients were discharded or died. The correlation between predictors (some patient characteristics on admission) and outcome (mortality) were evaluated using univariate analysis, and then proceeded to multivariable logistic regression analysis. P < 0.05 is considered statistically significant. Results: sixty patients with severe leptospirosis as a main diagnosis were evaluated. Fifty-five subjects were eligible for analysis, male patients 37 (67.3%) and mean age 42 +/- 15 years old. Pulmonary involvement was presence in 7 patients (12.7%). In univariate analysis only the presence of meningismus and pulmonary involvement were associated with mortality (p=0.001 and 0.006 respectively). In multivariable logistic regression, pulmonary involvement was independently a strong predictor of mortality (OR 9.9 95% CI (1.17 - 84.03), p=0.035). Conclusion: pulmonary involvement at admission is a strong predictor of mortality among patients with severe leptospirosis.en_US
dc.description.affiliationDepartment of Internal Medicine, Faculty of Medicine, Gadjah Mada University-Dr. Sardjito Hospital. Jl. Kesehatan Sekip no. 1, Yogyakarta.en_US
dc.identifier.citationBudiono E, Sumardi , Riyanto BS, Hisyam B, Hartopo AB. Pulmonary involvement predicts mortality in severe leptospirosis patients. Acta Medica Indonesiana. 2009 Jan; 41(1): 11-4en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/47159
dc.language.isoengen_US
dc.subject.meshLeptospirosisen_US
dc.subject.meshPulmonary Edemaen_US
dc.subject.meshLeptospirosis-mortalityen_US
dc.titlePulmonary involvement predicts mortality in severe leptospirosis patients.en_US
dc.typeJournal Articleen_US
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