Phytochemical screening and Antimicrobial activity of the leaves of Memecylon umbellatum burm F.
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Date
2011-03
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Abstract
An ethnomedicinal plant, Memecylon umbellatum Burm. f., was investigated for preliminary
phytochemical screening and antimicrobial activity. Preliminary phytochemical screening of
various extracts of the leaves revealed the presence of various classes of compounds such as
amino acids, carbohydrates, flavonoids, gum, oil & resins, proteins, phenolic groups, saponins,
steroids, tannins and terpenoids. Bioassay of antimicrobial activity of leaves of petroleum ether,
chloroform and ethanol extracts showed significant activity against the human pathogens such as
Streptococcus pneumoniae causing brain abscesses, pneumonia and septic arthritis, Proteus
vulgaris, Pseudomonas aeruginosa causing urinary tract infections and septicaemia, Salmonella
typhi causing typhoid fever, Vibrio species causing diarrheal infections and the fungus Candida
albicans. The antimicrobial activity of the petroleum ether, chloroform and ethanolic leaf extract
showed concentration-dependent activity against all the tested bacteria with the zone of inhibition
at various concentrations. Thus the findings revealed the medicinal potential of Memecylon
umbellatum against various infectious diseases to develop a drug.
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Keywords
Ethnomedicine, Memecylon umbellatum, phytochemistry, antimicrobial activity, human pathogens, drug development
Citation
Murugesan Subban, Pannerselvam Annamalai, Tangavelou Arumugame Chanemougame. Phytochemical screening and Antimicrobial activity of the leaves of Memecylon umbellatum burm F. Journal of Applied Pharmaceutical Science. 2011 Mar; 1(1): 42-45.