Application of six sigma metrics and method decision charts in improvising clinical Chemistry laboratory performance enhancement

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dc.contributor.authorAggarwal, Kavitaen_US
dc.contributor.authorPatra, Sauraven_US
dc.contributor.authorAcharya, Viyatprajnaen_US
dc.contributor.authorAgrawal, Maheshen_US
dc.contributor.authorMahapatra, Sri Krushnaen_US
dc.date.accessioned2020-04-09T07:42:52Z
dc.date.available2020-04-09T07:42:52Z
dc.date.issued2019-09
dc.description.abstractBackground: Six sigma is a powerful tool which can be used by laboratories for assessing the method quality, optimizing Quality Control (QC) procedure, change the number of rules applied, and frequency of controls run .The aim of this study was to quantify the defects or errors in the analytical phase of laboratory testing by sigma metrics and then represent the sigma value in Method Decision Chart.Methods: A retrospective study was conducted in a tertiary care hospital in Bhubaneswar, India. The clinical chemistry laboratory has been NABL accredited for the past 5 years and strictly quality checked. Internal and external quality control data was collected for a period of six months from January - June 2018 for 20 biochemical analytes. Sigma metrics for each parameter was calculated and plotted on method decision chart.Results: The sigma metrics for level 2 indicated that 6 out of the 20 analytes qualified Six Sigma quality performance. Of these seven analytes failed to meet minimum sigma quality performance with metrics less than three and another seven analytes performance with sigma metrics was between three and six. For level 3, the data collected indicated that seven out of 20 analytes qualified Six Sigma quality performance, six analytes had sigma metrics less than 3 and seven analytes had sigma metrics between 3 and 6.Conclusion: In our study Sigma value was highest for amylase and lowest for potassium. Use of alternative methods and/ or change of reagents can be done for potassium to bring the sigma value within an acceptable range.en_US
dc.identifier.affiliationsDepartment of Biochemistry, Kalinga Institute of Medical Sciences, KIIT University, Bhubaneswar, Odisha, Indiaen_US
dc.identifier.affiliationsDepartment of Biochemistry, Institute of Medical Sciences & SUM Hospital, Bhubaneswar Siksha ‘O’ Anusandhan University, Odisha, Indiaen_US
dc.identifier.affiliationsDepartment of Anaesthesiology, Utkal Institute of Medical Sciences, Bhubaneswar, Odisha, Indiaen_US
dc.identifier.citationAggarwal Kavita, Patra Saurav, Acharya Viyatprajna, Agrawal Mahesh, Mahapatra Sri Krushna. Application of six sigma metrics and method decision charts in improvising clinical Chemistry laboratory performance enhancement. International Journal of Advances in Medicine. 2019 Sep; 6(5): 1531-1534en_US
dc.identifier.issn2349-3925
dc.identifier.issn2349-3933
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/194454
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber5en_US
dc.relation.volume6en_US
dc.source.urihttps://dx.doi.org/10.18203/2349-3933.ijam20194155en_US
dc.subjectBiasen_US
dc.subjectImprecisionen_US
dc.subjectMethod decision charten_US
dc.subjectQuality controlen_US
dc.subjectQuality Goal Indexen_US
dc.subjectSigma metricsen_US
dc.titleApplication of six sigma metrics and method decision charts in improvising clinical Chemistry laboratory performance enhancementen_US
dc.typeJournal Articleen_US
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