Extensive intestinal metaplasia of renal pelvis: Report of a case and literature review.
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Date
2015-10
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Abstract
Transformation of the urothelium to the intestinal type of epithelium is rare in the
pelvis with very few cases reported in the literature. The present study reports
extensive intestinal metaplasia of the pelvi-calyceal system without residual
urothelium in a 35-years-old woman with a 2 years history of renal calculi. Right
- sided Nephrectomy was undertaken. Immunohistochemistry of the metaplastic
epithelium revealed positive expression of CK20, low Ki-67 index and negative
expression of p53. In this patient long standing metaplastic changes did not
progress to adenocarcinoma which indicates that extensive intestinal metaplasia
is not always associated with malignancy.
Description
Keywords
Intestinal metaplasia, nephrolithiasis, pelvi-calyceal system
Citation
Shukla Prakriti, Gulwani Hanni V. Extensive intestinal metaplasia of renal pelvis: Report of a case and literature review. Indian Journal of Pathology & Microbiology. 2015 Oct-Dec 58(4): 483-486.