Inhibitory effect of gonadotropin releasing hormone in the uterus of rat.
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Date
1985-03
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Abstract
Estradiol-induced incorporation of radioactive uridine and leucine into the uterus
of rat was inhibited by simultaneous treatment with an analogue of gonadotropin releasing
hormone. The inhibitory action of gonadotropin releasing hormone was not mediated
through modulation of estradiol receptor content. However, estradiol-induced increase in the
level of poly(A) polymerase was inhibited by gonadotropin releasing hormone analogue,
indicating that the inhibitory effect might involve post-transcriptional phenomenon.
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Keywords
Gonadotropin releasing hormone, RNA and protein synthesis, estradiol receptors, poly(A) polymerase
Citation
Rao I M, Reddy R L, Raju V S, Reddy P R K. Inhibitory effect of gonadotropin releasing hormone in the uterus of rat. Journal of Biosciences. 1985 Mar; 7(2): 153-159.