Evaluation of Intrathecal Bupivacaine with Bupivacaine and Nalbuphine For Post- Operative Analgesia in Inguinal Hernia Repair Surgery

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dc.contributor.authorChole, Minakshi P.en_US
dc.contributor.authorBhalke, Asmitaen_US
dc.contributor.authorNandanvankar, N. K.en_US
dc.contributor.authorYennawar, S.Den_US
dc.date.accessioned2020-01-02T06:09:10Z
dc.date.available2020-01-02T06:09:10Z
dc.date.issued2019-11
dc.description.abstractBackground: Inguinal hernia repair is one of the common surgeries performed in general population under spinal anesthesia. Though Spinal anesthesia is relatively safe it has a short duration of action and can’t be used when the surgery is expected to be prolonged. To overcome this drawback various adjuvants are being increasingly used. Spinal anesthesia with 0.5% hyperbaric Bupivacaine, along with adjuvants, is routinely administered for lower abdominal surgeries. Intrathecal Nalbuphine added to Bupivacaine (0.5% Hyperbaric) has the potential to provide good intraoperative analgesia & prolongs early post-operative analgesia. Methods: 30 ASA I and II patients of age group 20-65 years, scheduled for inguinal hernia repair were included in this study on the basis of a predefined inclusion and exclusion criteria. Patients were randomized in two equal groups of 30 each. Group I patients received bupivacaine 0.5% heavy 3.1 ml + intrathecal nalbuphine 0.4 ml (0.4mg) whereas patients in group II received bupivacaine 0.5% heavy 3.1ml + 0.4ml NS. Onset of sensory and motor blockade, duration of analgesia, need for rescue analgesia, hemodynamic parameters and incidence of adverse effects was compared in both the groups. P value less than 0.05 was taken as statistically significant. Results: Demographic parameters such as gender, height, weight and BMI were found to be comparable in both the groups. Moreover, ASA grades, duration of surgery, Time of onset of sensory and motor blocks were also found to be comparable. Duration of sensory and motor block and duration of postoperative analgesia was found to be significantly more in group I as compared to group II. Hemodynamic parameters and incidence of side effects was found to be comparable in both the groups. Conclusion: Addition of nalbuphine to Bupivacaine in patients undergoing inguinal hernia repair under spinal anesthesia is associated with prolonged duration of sensory and motor blockade as well as reduced need for giving rescue analgesia without increase in incidence of side effects.en_US
dc.identifier.affiliationsSenior Resident, Dr. SCGMC, Nandeden_US
dc.identifier.affiliationsAssociate Professor, Dr. SCGMC, Nandeden_US
dc.identifier.affiliationsProfessor and Head, SCGMC Nanded.en_US
dc.identifier.citationChole Minakshi P., Bhalke Asmita, Nandanvankar N. K., Yennawar S.D. Evaluation of Intrathecal Bupivacaine with Bupivacaine and Nalbuphine For Post- Operative Analgesia in Inguinal Hernia Repair Surgery. Annals of International medical and Dental Research. 2019 Nov; 5(6): 10-16en_US
dc.identifier.issn2395-2822
dc.identifier.issn2395-2814
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/189125
dc.languageenen_US
dc.publisherSociety for Health Care & Research Developmenten_US
dc.relation.issuenumber6en_US
dc.relation.volume5en_US
dc.source.urihttps://doi.org/10.21276/aimdr.2019.5.6.AN3en_US
dc.subjectInguinal Hernia Repairen_US
dc.subjectSpinal Anesthesiaen_US
dc.subjectBupivacaineen_US
dc.subjectNalbuphineen_US
dc.titleEvaluation of Intrathecal Bupivacaine with Bupivacaine and Nalbuphine For Post- Operative Analgesia in Inguinal Hernia Repair Surgeryen_US
dc.typeJournal Articleen_US
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