Isolation of Fluoroquinolones Resistant Salmonella spp. from Stool Samples of Patients Attending General Hospital Minna and Ibrahim Badamasi Babangida Specialist Hospital, Minna, Nigeria

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dc.contributor.authorAngulu, C. Nen_US
dc.contributor.authorAdabara, N. Uen_US
dc.contributor.authorMamman, G. Pen_US
dc.contributor.authorOlusola, L. Fen_US
dc.contributor.authorJesse, I. Aen_US
dc.contributor.authorKin, Aen_US
dc.contributor.authorPeace, O. O.en_US
dc.date.accessioned2023-06-27T06:26:12Z
dc.date.available2023-06-27T06:26:12Z
dc.date.issued2022-05
dc.description.abstractTyphoid fever continues to be a major health problem despite the use of antibiotics and the development of newer antibacterial drugs. This study aim was to isolate fluoroquinolones resistant Salmonella spp from stool samples of informed and consenting patient attending General Hospital and Ibrahim Badamasi Babangida Specialist Hospital in Minna Niger State Nigeria. A total 450 stool samples were collected from the Hospital. The results showed that 69 (30.4%) of the sample collected were positive for Salmonella species. On the basis of age children within the age range of 0-10 recorded the highest prevalence of 22.7% followed by age range 51-60 having the prevalence of 19.4%, age range >60 had the prevalence of 16.7% and age range 21-30 and 11-20 had a similar prevalence of (10.1% and 10.3% respectively) while age range 31-40 had the least prevalence of 7.8%. There were 69 isolates of Salmonella species Identified, 65(94.2%) were Resistant to the antibiotics used. The highest resistance was shown to Pefloxacin 62 (89.9%) and the lowest was shown to Ciprofloxacin 27 (39.1%). Salmonella species exhibited 52 antibiotic resistant patterns for the ten antibiotics tested with multiple antibiotic resistance index (MARI) ranging from 0.3-1.0. Molecular analysis was carried out on 5 representative isolates to identify their strains. Polymerase chain reaction (PCR) assay showed the identified Salmonella strains were Salmonella enterica subsp. arizonae strain ATCC 13314, Salmonella enterica subsp. enterica serovar Typhi strain 2018K-0756, Salmonella bongori strain SL18, Salmonella bongori strain GH3Rp and Salmonella enterica subsp. arizonae strain ATCC 13314, they all showed resistance to fluoroquinolones.en_US
dc.identifier.affiliationsDepartment of Microbiology, School of Life Sciences, Federal University of Technology, Minna, Niger State, Nigeriaen_US
dc.identifier.affiliationsDepartment of Microbiology, School of Life Sciences, Federal University of Technology, Minna, Niger State, Nigeriaen_US
dc.identifier.affiliationsDepartment of Biology, Faculty of Natural Sciences, Nigeria Army University, Biu Borno State, Nigeria.en_US
dc.identifier.affiliationsDepartment of Biological Sciences, School of Natural and Applied Sciences, Niger State Polytechnic, Zungeru, Nigeria.en_US
dc.identifier.affiliationsDepartment of Biological Sciences, Taraba State University, Jalingo, Taraba State, Nigeria.en_US
dc.identifier.affiliationsDepartment of Biological Sciences, School of Natural and Applied Sciences, Niger State Polytechnic, Zungeru, Nigeria.en_US
dc.identifier.affiliationsDepartment of Biological Science Laboratory Technology, Auchi Polytechnic, Auchi, Edo State, Nigeria.en_US
dc.identifier.citationAngulu C. N, Adabara N. U, Mamman G. P, Olusola L. F, Jesse I. A, Kin A, Peace O. O.. Isolation of Fluoroquinolones Resistant Salmonella spp. from Stool Samples of Patients Attending General Hospital Minna and Ibrahim Badamasi Babangida Specialist Hospital, Minna, Nigeria. Sciencedomain International. 2022 May; 32(2): 1-10en_US
dc.identifier.issn2456-7043
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/217193
dc.languageenen_US
dc.publisherMicrobiology Research Journal Internationalen_US
dc.relation.issuenumber2en_US
dc.relation.volume32en_US
dc.source.urihttps://doi.org/10.9734/mrji/2022/v32i230368en_US
dc.subjectSalmonellaen_US
dc.subjectantibioticsen_US
dc.subjectfluoroquinolonesen_US
dc.subjectresistanceen_US
dc.subjecttyphoid feveren_US
dc.titleIsolation of Fluoroquinolones Resistant Salmonella spp. from Stool Samples of Patients Attending General Hospital Minna and Ibrahim Badamasi Babangida Specialist Hospital, Minna, Nigeriaen_US
dc.typeJournal Articleen_US
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