Coronary Artery Disease in Young Indians: A Different Entity

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dc.contributor.authorBhat, Keshavamurthy Ganapathyen_US
dc.contributor.authorKamal, Hasan Kandanuruen_US
dc.contributor.authorKumar, Anilen_US
dc.contributor.authorSwamy, Ajay Jagannathen_US
dc.contributor.authorKumar, Mahesh Nalinen_US
dc.contributor.authorSharma, Prafullen_US
dc.date.accessioned2020-09-24T07:26:05Z
dc.date.available2020-09-24T07:26:05Z
dc.date.issued2019-09
dc.description.abstractObjective: To study the angiographic profile, treatment andoutcome of Coronary Artery Disease (CAD) in young (< 45years) individuals in India.Methods: Consecutive 132 young adults with CAD reporting totwo tertiary care centres over a period of 1 ½ years wereenrolled as a case control observational study. Subjects whopresented with acute coronary syndrome (ACS), chronic stableangina (CSA), Heart failure or AsymptomaticElectrocardiogram (ECG) abnormalities but confirmed CAD onCoronary Angiogram (CAG) were included. Angiographicprofile, treatment and outcome were analysed with a follow upof one year.Results: Risk factors of abdominal obesity, lipoprotein (a)[Lp(a)] and tobacco consumption were significantly higher instudy group. ST elevation Myocardial Infarction (STEMI) wasthe commonest presentation (71.21%). Single vessel disease(56.06 %) was the commonest angiographic profile with LeftAnterior Descending Artery (LAD) involvement (40.91%).Primary Angioplasty in Myocardial Infarction (PAMI) was donein 42.5% of STEMI and Thrombolysis in 48.9%. Three types ofcoronary involvement were noticed with Type I having discretelesions/thrombus and Type III having multiple segment/arteryinvolvement with differing risk factor profile and outcome.Diffuse and more severe CAD was associated with tobaccouse, abdominal obesity and elevated Lp (a). Late presentation,diffuse disease and persistence of smoking predicted pooreroutcome.Conclusions: CAD in Young commonly presents with AcuteMI and single vessel LAD involvement. Less than half haveaccess to PAMI. Most require stenting although selectedpatients do well with intracoronary thrombolysis. Delayedtreatment and failure to modify risk factors portend badprognosis.en_US
dc.identifier.affiliationsMD, DNB (Med), DM, DNB (Cardiology), FACC, FSCAI,Senior Advisor (Medicine) and Cardiologist, Command Hospital (AF), Bengaluru, Karnataka, India.en_US
dc.identifier.affiliationsMD, Assistant Professor, Department of General Medicine, Ayaan Institute of Medical Sciences, Teaching Hospital and Research Centre, Kanakamamidi (v), Moinabad Mandal, Ranga Reddy District, Telangana, India.en_US
dc.identifier.affiliationsMD, DM, Senior Advisor (Medicine) and Cardiologist, Command Hospital, Chandimandir, Haryana, India.en_US
dc.identifier.affiliationsMD, DNB (Medicine), DM, FSCAI, Senior Advisor (Medicine) and Cardiologist, Military Hospital, Cardio Thoracic Centre, Pune, Maharastra, India.en_US
dc.identifier.affiliationsMD, DNB, FACC, FSCAI, Head of Department of Cardiology, Base Hospital, Delhi, India.en_US
dc.identifier.affiliationsMD, DM, FACC, Classified Specialist (Medicine) and Cardiologist, Base Hospital, Delhi, Indiaen_US
dc.identifier.citationBhat Keshavamurthy Ganapathy, Kamal Hasan Kandanuru, Kumar Anil, Swamy Ajay Jagannath, Kumar Mahesh Nalin, Sharma Prafull. Coronary Artery Disease in Young Indians: A Different Entity. International Journal of Medical Research Professionals. 2019 Sep; 5(5): 1-10en_US
dc.identifier.issn2454-6364
dc.identifier.issn2454-6356
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/203411
dc.languageenen_US
dc.publisherIbn Sina Academy of Medieval Medicine & Sciencesen_US
dc.relation.issuenumber5en_US
dc.relation.volume5en_US
dc.source.urihttps://dx.doi.org//10..21276/ijmrp.2019.5.5.001en_US
dc.subjectCoronary Artery Diseaseen_US
dc.subjectYoungen_US
dc.subjectRisk Factorsen_US
dc.subjectLipoprotein (a)en_US
dc.subjectAbdominal Obesity.en_US
dc.titleCoronary Artery Disease in Young Indians: A Different Entityen_US
dc.typeJournal Articleen_US
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