A prospective study on emergence of mucormycosis in recently recovered COVID-19 patients

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dc.contributor.authorLandge, S.en_US
dc.contributor.authorMenon, S.en_US
dc.contributor.authorChande, C.en_US
dc.contributor.authorKulkarni, M.en_US
dc.contributor.authorBhilkar, K.en_US
dc.contributor.authorBade, J.en_US
dc.contributor.authorJoshi, A.en_US
dc.date.accessioned2024-09-24T10:51:30Z
dc.date.available2024-09-24T10:51:30Z
dc.date.issued2023-07
dc.description.abstractBackground: Mucormycosis is an angio-invasive fungal infection with high morbidity and mortality. This infection seems to be increasing during the second wave of COVID-19. Objectives of this study were to identify and characterise the fungal species causing post-covid-mycosis, to analyze the cases for underlying co-morbidities if any and to correlate the associated risk factors with the progression of disease. Methods: Prospective observational study which constituted conventional fungal culture of 188 tissue specimens collected from clinically suspected mucormycosis patients who had history of COVID. Results: This study noted the occurrence of disease with predominance of males (72.03%). Most common symptoms were facial/periorbital swelling, followed by facial pain and headache. Among co-morbid conditions, diabetes mellitus was the most common (71.17%). Use of steroids (65.25%), antivirals therapy (22.86%), oxygen support (11.86%) used in management of COVID patients were found to be risk factors in post-covid-mucormycosis. radiological diagnosis showed involvement of paranasal sinuses (77.11%), followed by orbit (16.94%) and brain (5.90%). Mucor spp. was isolated in 21 cases. Although commonest fungus isolated was Aspergillus, analysis of the data for last 5 years showed a significant rise of Mucormycosis cases. Mortality was seen in 17.79% cases. Conclusions: Fungal aetiology should be kept in mind in patients with above clinical presentations with history of recent COVID-19 infection especially who received steroids.en_US
dc.identifier.affiliationsDepartment of Microbiology, Grant Government Medical College and Sir J.J. Group of Hospitals, Mumbai, Maharashtra, Indiaen_US
dc.identifier.affiliationsDepartment of Microbiology, Grant Government Medical College and Sir J.J. Group of Hospitals, Mumbai, Maharashtra, Indiaen_US
dc.identifier.affiliationsDepartment of Microbiology, Grant Government Medical College and Sir J.J. Group of Hospitals, Mumbai, Maharashtra, Indiaen_US
dc.identifier.affiliationsDepartment of Microbiology, Grant Government Medical College and Sir J.J. Group of Hospitals, Mumbai, Maharashtra, Indiaen_US
dc.identifier.affiliationsDepartment of Microbiology, Grant Government Medical College and Sir J.J. Group of Hospitals, Mumbai, Maharashtra, Indiaen_US
dc.identifier.affiliationsDepartment of Microbiology, Grant Government Medical College and Sir J.J. Group of Hospitals, Mumbai, Maharashtra, Indiaen_US
dc.identifier.affiliationsDepartment of Microbiology, Grant Government Medical College and Sir J.J. Group of Hospitals, Mumbai, Maharashtra, Indiaen_US
dc.identifier.citationLandge S., Menon S., Chande C., Kulkarni M., Bhilkar K., Bade J., Joshi A.. A prospective study on emergence of mucormycosis in recently recovered COVID-19 patients. International Journal of Research in Medical Sciences. 2023 Jul; 11(7): 2498-2502en_US
dc.identifier.issn2320-6071
dc.identifier.issn2320-6012
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/234467
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber7en_US
dc.relation.volume11en_US
dc.source.urihttps://doi.org/10.18203/2320-6012.ijrms20232089en_US
dc.subjectAspergillosisen_US
dc.subjectCOVID-19en_US
dc.subjectDiabetes mellitusen_US
dc.subjectPost-covid-mucormycosisen_US
dc.subjectSteroiden_US
dc.titleA prospective study on emergence of mucormycosis in recently recovered COVID-19 patientsen_US
dc.typeJournal Articleen_US
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