Levamisole Monotherapy in Treatment of Oral Lichen Planus-A Clinical Study

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dc.contributor.authorPushpanjalien_US
dc.contributor.authorDayanandamen_US
dc.contributor.authorSultana, Juweriaen_US
dc.date.accessioned2019-12-02T09:49:02Z
dc.date.available2019-12-02T09:49:02Z
dc.date.issued2017-11
dc.description.abstractBackground Oral lichen planus is a chronic inflammatory disease of oral mucosa which rarely undergoes spontaneous remission and has potential for malignant transformation. There are several different kinds of treatment that have been used to treat chronic oral lichen planus. Most commonly advised treatment is steroid therapy to treat oral lichen planus either in topical form or systemically. As steroid therapy has various underlying adverse effects other alternative drug has to be used in the treatment of oral lichen planus. Objective The aim of the study is to evaluate the efficacy of levamisole monotherapy in oral lichen planus. Methods Seven patients who had oral lichen planus were treated with levamisole 50 mg thrice daily for 3 consecutive days and not administered for the following 4 days. Result After 2 weeks of treatment, four patients reported with partial response, three patients had no response and no patients showed clearance of the lesion. Furthermore, after 2 months of treatment, five patients showed clearance of lesion, one patient showed partial response and one patient had no response to therapy. There were no significant side effects noted. Conclusion Levamisole therapy can be a substitute to steroid therapy in treating oral lichen planus in patients who can't take steroids.en_US
dc.identifier.affiliationsAssociate Professor, Department of Oral and Maxillofacial Surgery, GDC & H, RIMS, Kadapa, Andhra Pradesh, Indiaen_US
dc.identifier.affiliationsAssistant Professor, Department of Oral Medicine and Radiology, GDC & H, RIMS, Kadapa, Andhra Pradesh, India, sindhudentalsdnr@gmail.comen_US
dc.identifier.affiliationsIII Year Post Graduate, Department of Oral Medicine and Radiology, GDC & H, RIMS, Kadapa, Andhra Pradesh, India, juwerias1@gmail.comen_US
dc.identifier.citationPushpanjali, Dayanandam, Sultana Juweria. Levamisole Monotherapy in Treatment of Oral Lichen Planus-A Clinical Study. Indian Journal of Mednodent and Allied Sciences. 2017 Nov; 5(3): 190-192en_US
dc.identifier.issn2347-6192
dc.identifier.issn2347-6206
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/186096
dc.languageenen_US
dc.publisherAssociation of Medical Dental and Allied Sciencesen_US
dc.relation.issuenumber3en_US
dc.relation.volume5en_US
dc.source.urihttps://dx.doi.org/10.5958/2347-6206.2017.00031.0en_US
dc.subjectOral lichen planusen_US
dc.subjectLevamisoleen_US
dc.titleLevamisole Monotherapy in Treatment of Oral Lichen Planus-A Clinical Studyen_US
dc.typeJournal Articleen_US
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