Does buprenorphine maintenance improve the quality of life of opioid users.

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dc.contributor.authorDhawan, A
dc.contributor.authorChopra, A
dc.date.accessioned2013-08-05T05:27:08Z
dc.date.available2013-08-05T05:27:08Z
dc.date.issued2013-01
dc.description.abstractBackground & objectives: The quality of life (QOL) of substance abusers is known to be severely impaired. Information on impact of opioid maintenance treatment on the QOL of opioid dependent subjects though available from the developed countries, is lacking from India. This study was carried out to assess the impact of buprenorphine maintenance treatment on the quality of life (QOL) of opioid dependent subjects at nine months follow up. Methods: Based on specified inclusion criteria a total of 231 subjects were recruited from five participating centres across India. They received sublingual buprenorphine as a directly observed therapy along with brief psychosocial intervention (provided in groups of 8-10 subjects) after intake in to the study. The WHOQOL-BREF scale domain scores obtained at baseline were compared to domain scores at nine months follow up. Results: At nine months follow up, among the 64.1 per cent retained in buprenorphine maintenance, there was a significant (P<0.001) decline in opioid use from 24.9 ± 10.1 days at baseline to 1.7 ± 4.7 days at nine months follow up and improvements in score of the four WHOQOL-BREF domains (Physical, Psychological, Social relationships and Environment). Interpretation & conclusions: The results showed the beneficial effects of buprenorphine maintenance treatment in improving the QOL of opioid-dependent subjects at nine month follow up. These results point towards the need for an expanded nation-wide provision of buprenorphine maintenance treatment as a harm reduction strategy for the opioid dependent population.en_US
dc.identifier.citationDhawan A, Chopra A. Does buprenorphine maintenance improve the quality of life of opioid users. Indian Journal of Medical Research. 2013 Jan; 137(1): 130-135.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/147698
dc.language.isoenen_US
dc.source.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657876/?report=classicen_US
dc.subjectBuprenorphine maintenanceen_US
dc.subjectIndiaen_US
dc.subjectopioid usersen_US
dc.subjectquality of lifeen_US
dc.titleDoes buprenorphine maintenance improve the quality of life of opioid users.en_US
dc.typeArticleen_US
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