Impact evaluation of iron & iodine fortified salt.

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dc.contributor.authorNair, K Men_US
dc.contributor.authorBrahmam, G Nen_US
dc.contributor.authorRanganathan, Sen_US
dc.contributor.authorVijayaraghavan, Ken_US
dc.contributor.authorSivakumar, Ben_US
dc.contributor.authorKrishnaswamy, Ken_US
dc.date.accessioned1998-11-24en_US
dc.date.accessioned2009-05-27T08:34:06Z
dc.date.available1998-11-24en_US
dc.date.available2009-05-27T08:34:06Z
dc.date.issued1998-11-24en_US
dc.description26 references.en_US
dc.description.abstractAs a novel approach to tackle the problems of iron deficiency anaemia and iodine deficiency disorders (IDDs), which often coexist, the National Institute of Nutrition has developed iron and iodine fortified common salt (double fortified salt-DFS) as a public health measure. This salt has undergone a battery of laboratory and field tests to evaluate its feasibility for use in a national programme. The DFS is designed to provide 1 mg of iron and 15 micrograms of iodine per gram of common salt. This was made possible by the inclusion of a polyphosphate stabilizer, sodium hexametaphosphate (SHMP) at 1 per cent level. The stability of iron and iodine was found to be good up to 6 months. However, the stability of iodine depended upon the quality of the salt used for fortification. The biological effects of long-term consumption of DFS were evaluated in experimental rats and in field trials. Both iron and iodine from the salt were found to be biologically available in regenerating haemoglobin and in increasing excretion of iodine in urine. When this salt was tested in tribal villages endemic for goitre and iron deficiency anaemia, the bioresponse was good with regard to the iodine status but was not uniform in all segments with regard to iron, probably due to confounding variables. In a study carried out in residential school children where such variables did not exist, DFS was found to have significant impact on haemoglobin status in anaemic children and improved their urinary iodine excretion. The consumption of DFS for 2 yr did not have any adverse effects in school children as well as in the tribal population. Parameters related to calcium homeostasis were not altered in children receiving DFS. Histopathological examination of tissues and radiological examination of bone did not reveal any abnormality in DFS fed rats. Similarly serum and urinary parameters related to calcium and phosphorus were not altered in DFS fed rats. Therefore, DFS is presented as a feasible and effective strategy to control the double deficiency of iron and iodine in our community.en_US
dc.description.affiliationNational Institute of Nutrition (ICMR), Hyderabad.en_US
dc.identifier.citationNair KM, Brahmam GN, Ranganathan S, Vijayaraghavan K, Sivakumar B, Krishnaswamy K. Impact evaluation of iron & iodine fortified salt. Indian Journal of Medical Research. 1998 Nov; 108(): 203-11en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/24899
dc.language.isoengen_US
dc.source.urihttps://icmr.nic.in/ijmr/ijmr.htmen_US
dc.subject.meshAnimalsen_US
dc.subject.meshChilden_US
dc.subject.meshFood, Fortifieden_US
dc.subject.meshHumansen_US
dc.subject.meshIodine --administration & dosageen_US
dc.subject.meshIron --administration & dosageen_US
dc.subject.meshRatsen_US
dc.subject.meshSodium Chlorideen_US
dc.titleImpact evaluation of iron & iodine fortified salt.en_US
dc.typeJournal Articleen_US
dc.typeReviewen_US
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