Carriage of ESBL and AmpC-Positive Enterobacteriaceae in Gastrointestinal Tract of Healthy Community Subjects and Hospitalized Patients and Detection of blaCTX-M Gene in ESBL Positive Isolates.
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Date
2015-06
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Abstract
Aim: The study aimed at analyzing ESBL and AmpC
positive Enterobacteriaceae in the gastrointestinal tracts of
healthy community subjects and hospitalized patients and
detection of blaCTX-M type gene in ESBL positive isolates.
Methods: Bacteria were isolated from stool samples of the
study population. Production of ESBL-type beta-lactamases
was screened by double-disk synergy test as well as
automated system, and AmpC enzyme production was
detected by the AmpC disk test. ESBL positive isolates were
subjected to detection of the blaCTX-M gene. Results: A total
of 792 stool samples (50% from healthy subjects and 50%
from hospitalized patients) were studied. The prevalence
rates of ESBL-positive Enterobacteriaceae were 9.3% in
hospitalized patients and 4.4% in healthy community
subjects. Production of the AmpC enzyme was detected in
Description
Keywords
AmpC, Enterobacteriaceae, blaCTXM, ESBL
Citation
Rashid Mohd , Modi Syamal, Sarwat Tarana, Chander Yogesh, Rastogi Vichal, Manocha Harmesh. Carriage of ESBL and AmpC-Positive Enterobacteriaceae in Gastrointestinal Tract of Healthy Community Subjects and Hospitalized Patients and Detection of blaCTX-M Gene in ESBL Positive Isolates. Indian Medical Gazette. 2015 Jun; 149(6): 212-218.