Comparison of corneal endothelial cell loss during phacoemulsification using continuous anterior chamber infusion versus those using ophthalmic viscosurgical device: randomized controlled trial.

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dc.contributor.authorNayak, B Ken_US
dc.contributor.authorJain, Elesh Kumaren_US
dc.date.accessioned2009-03-25en_US
dc.date.accessioned2009-05-29T09:20:36Z
dc.date.available2009-03-25en_US
dc.date.available2009-05-29T09:20:36Z
dc.date.issued2009-03-25en_US
dc.description.abstractAIM: We conducted this study to evaluate and compare corneal endothelial cell loss between phacoemulsification with continuous anterior chamber infusion using anterior chamber maintainer (ACM) and phacoemulsification using ophthalmic viscosurgical device (OVD). MATERIALS AND METHODS: This was a prospective, randomized controlled trial. Fifty eyes of 47 patients of senile cataract undergoing phacoemulsification were included. Patients were randomly allocated into two groups of 25 eyes each. Cataract surgery was performed by phacoemulsification with anterior chamber (AC) continuous infusion with balanced salt solution (BSS) plus and ACM without OVD in Group A, and in Group B, phacoemulsification was performed using OVD with BSS plus. Corneal endothelial cell count and pachymetry were performed preoperatively and postoperatively on day 1, day 7, and day 30. The mean increase in pachymetry was 4.86%, 2.94%, and 1.94%, (Group A) and 5.95%, 3.94%, and 0.51%, (Group B) on first, seventh, and 30 th postoperative day respectively. The difference between the percentage increase in pachymetry between the two groups was not significant at day 1 ( P = 0.441), day 7 ( P = 0.298), and day 30 ( P =0.174) postoperatively. The density of endothelial cells decreased postoperatively (day 30) by 7.38% (Group A) and 7.47% (Group B) without any significant statistical difference ( P = 0.983) between two groups. CONCLUSION: Use of ACM for continuous AC infusion and omission of OVD during phacoemulsification did not cause significant difference in corneal swelling or endothelial cell loss in the immediate postoperative period up to one month.en_US
dc.description.affiliationOphthalmology Department, P.D. Hinduja National Hospital and MRC, Veer Savarkar Marg, Mumbai - 400 016, India. drbknayak@gmail.comen_US
dc.identifier.citationNayak BK, Jain EK. Comparison of corneal endothelial cell loss during phacoemulsification using continuous anterior chamber infusion versus those using ophthalmic viscosurgical device: randomized controlled trial. Indian Journal of Ophthalmology. 2009 Mar-Apr; 57(2): 99-103en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/71490
dc.language.isoengen_US
dc.source.urihttps://www.ijo.inen_US
dc.source.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2684437/en_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAged, 80 and overen_US
dc.subject.meshAnterior Chamber --drug effectsen_US
dc.subject.meshBicarbonates --administration & dosageen_US
dc.subject.meshCell Counten_US
dc.subject.meshCorneal Diseases --etiologyen_US
dc.subject.meshDrug Combinationsen_US
dc.subject.meshEndothelium, Corneal --pathologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshGlutathione --administration & dosageen_US
dc.subject.meshHumansen_US
dc.subject.meshHyaluronic Acid --administration & dosageen_US
dc.subject.meshIntraoperative Complicationsen_US
dc.subject.meshLens Implantation, Intraocularen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPhacoemulsification --methodsen_US
dc.subject.meshProspective Studiesen_US
dc.subject.meshViscosupplements --administration & dosageen_US
dc.titleComparison of corneal endothelial cell loss during phacoemulsification using continuous anterior chamber infusion versus those using ophthalmic viscosurgical device: randomized controlled trial.en_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
dc.typeRandomized Controlled Trialen_US
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