A pilot study to determine genetic polymorphism in Mycobacterium tuberculosis isolates in Central India.

Simple item page
dc.contributor.authorDesikan, P
dc.contributor.authorChauhan, D S
dc.contributor.authorSharma, P
dc.contributor.authorPanwalkar, N
dc.contributor.authorGautam, S
dc.contributor.authorKatoch, V M
dc.date.accessioned2012-12-21T04:31:18Z
dc.date.available2012-12-21T04:31:18Z
dc.date.issued2012-10
dc.description.abstractThis study was carried out to identify predominant spoligotypes responsible for transmission and prevalence of tuberculosis in central India since there is no data available about the genetic biodiversity of Mycobacterium tuberculosis isolates from patients with tuberculosis in this region. 35 strains of Mycobacterium tuberculosis were subjected to spoligotyping according to the standard protocol. A total of 25 strains out of the 35 (71.42%) could be grouped in to 6 clusters. The largest cluster comprised 8 isolates. Unique (Non-clustered) spoligotypes were seen in 10 isolates, Nine strains did not match the data base (Spol DB-4 data base). The results indicate that there may be a number of orphan strains unique to this geographical area. Further studies on a larger sample size derived from this area would help us delineate the epidemiology of Mycobacterium tuberculosis infection in this area.en_US
dc.identifier.citationDesikan P, Chauhan D S, Sharma P, Panwalkar N, Gautam S, Katoch V M. A pilot study to determine genetic polymorphism in Mycobacterium tuberculosis isolates in Central India. Indian Journal of Medical Microbiology. 2012 Oct-Dec; 30(4): 470-473.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/144013
dc.language.isoenen_US
dc.source.urihttps://www.ijmm.org/article.asp?issn=0255-0857;year=2012;volume=30;issue=4;spage=470;epage=473;aulast=Desikanen_US
dc.subjectGenetic polymorphismen_US
dc.subjectMycobacterium tuberculosisen_US
dc.subjectspoligotypingen_US
dc.subject.meshBacterial Typing Techniques --methods
dc.subject.meshGenotyping Techniques --methods
dc.subject.meshHumans
dc.subject.meshIndia --epidemiology
dc.subject.meshMycobacterium tuberculosis --classification
dc.subject.meshMycobacterium tuberculosis --genetics
dc.subject.meshPolymorphism, Genetic --genetics
dc.subject.meshTertiary Care Centers
dc.subject.meshTuberculosis --classification
dc.subject.meshTuberculosis --epidemiology
dc.subject.meshTuberculosis --genetics
dc.titleA pilot study to determine genetic polymorphism in Mycobacterium tuberculosis isolates in Central India.en_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
ijmm2012v30n4p470.pdf
Size:
460.38 KB
Format:
Adobe Portable Document Format
Description:
Journal article
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Indian Journal of Medical Microbiology