A series of choroidal melanoma in young patients: insights from a tertiary care facility

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dc.contributor.authorKumar, SVen_US
dc.contributor.authorKumar, Ven_US
dc.contributor.authorKumar, NVen_US
dc.contributor.authorSati, Aen_US
dc.contributor.authorBandopadhyay, S.en_US
dc.date.accessioned2025-08-13T11:21:18Z
dc.date.available2025-08-13T11:21:18Z
dc.date.issued2025-06
dc.description.abstractChoroidal melanoma is rare in young individuals and often presents at a later stage due to low clinical suspicion. This case series describes a group of young patients, all under the age of 30 years, who presented with advanced choroidal melanoma requiring enucleation. A prospective observational study was conducted from January 2019 to December 2023 at a tertiary care center. Twelve young patients diagnosed with choroidal melanoma were assessed. Patient’s demography, clinical presentation, tumor characteristics and histopathological findings were noted. Histopathologically tumors were classified as epithelioid, mixed and spindle cell type. The treatment protocol was devised based on the size, extent of the lesion and any involvement of systemic system. There were 10 females and 02 males. The mean age of patients in the current study was 23±3.5 years. Right eye was involved in 05 patients and left eye was involved in 07 patients. All patients had advanced choroidal melanoma at the time of presentation at our center. The mean basal diameter of the tumor was 21±2 mm and thickness were 11±1.5 mm. Primary enucleation with implant was the most common treatment modality in all patients. Epithelioid cell type choroidal melanoma was the commonest histology pattern was found in the current study. No mortality or death occurred at the end of 02 years follow-up in any patient. This series highlights the aggressive nature of choroidal melanoma in young individuals when diagnosed at an advanced stage. It emphasizes the importance of early clinical suspicion, timely referral, and appropriate imaging in any atypical choroidal lesion in the young population.en_US
dc.identifier.affiliationsCommand Hospital Eastern Command, Kolkata, West Bengal, Indiaen_US
dc.identifier.affiliationsDepartment of Anatomy, J. I. S.School of Medical Science and Research, Howrah, West Bengal, Indiaen_US
dc.identifier.affiliationsDepartment of Ophthalmology, Sri Devaraj UrsMedical College, Kolar, Karnataka, Indiaen_US
dc.identifier.affiliationsDepartment of Ophthalmology, Army Hospital Research andReferral, New Delhi, Indiaen_US
dc.identifier.affiliationsDepartmentof Ophthalmology,Command Hospital Eastern Command, Kolkata, West Bengal, Indiaen_US
dc.identifier.citationKumar SV, Kumar V, Kumar NV, Sati A, Bandopadhyay S.. A series of choroidal melanoma in young patients: insights from a tertiary care facility . International Journal of Clinical Trials. 2025 Jun; 12(2): 163-168en_US
dc.identifier.issn2349-3240
dc.identifier.issn2349-3259
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/253740
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber2en_US
dc.relation.volume12en_US
dc.source.urihttps://dx.doi.org/10.18203/2349-3259.ijct20251212en_US
dc.subjectYoungen_US
dc.subjectChoroidal melanomaen_US
dc.subjectIncidenceen_US
dc.subjectLargeen_US
dc.subjectEnucleationen_US
dc.subjectEpithelioiden_US
dc.titleA series of choroidal melanoma in young patients: insights from a tertiary care facilityen_US
dc.typeJournal Articleen_US
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