Seroepidemiology and active surveillance of dengue fever/dengue haemorrhagic fever in Delhi.

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dc.contributor.authorKurukumbi, Men_US
dc.contributor.authorWali, J Pen_US
dc.contributor.authorBroor, Sen_US
dc.contributor.authorAggarwal, Pen_US
dc.contributor.authorSeth, Pen_US
dc.contributor.authorHanda, Ren_US
dc.contributor.authorDhar, Len_US
dc.contributor.authorVajapayee, Men_US
dc.date.accessioned2001-03-03en_US
dc.date.accessioned2009-05-29T05:20:55Z
dc.date.available2001-03-03en_US
dc.date.available2009-05-29T05:20:55Z
dc.date.issued2001-03-03en_US
dc.description.abstractThe aims of the present study were to carry out surveillance for dengue virus infection in adults with short-duration fever, and serological study of dengue virus infection in persons without fever. Patients were divided into two groups. Group 1 included patients above 12 years of age with fever of 2-12 days duration without any apparent cause. Of these, patients who presented with fever for 2-5 days were included for virus isolation (group 1a) while those who presented within 6-12 days of the onset of fever were included for the dengue-specific IgM serology (group 1b). Group 2 included a sample of population belonging to all age groups but without pyrexia and blood was collected for dengue-specific IgG serology. Twenty-six patients were enrolled in group 1a over a period of 4 months (September to December, 1997). Of these, DEN1 was isolated in 5 cases. Group 1b included 182 patients, out of which 34 (18.68%) were positive for dengue-specific IgM antibodies. Significantly, all the positive cases were detected during the months of September to November. Retro-orbital pain was present in a significantly more number of IgM-positive cases as compared to IgM-negative cases. Group 2 included 125 cases without fever. The overall positivity for dengue-specific IgG antibodies was 77.6%, with the highest positivity of 100% in the age group of 31-40 years. It was concluded that dengue virus infection is endemic in and around Delhi with peak incidence between September and Novemver. The prevalent serotype during September and December 1997 was DEN1. Since previous epidemic of DHF was due to DEN2 type, isolation of DEN1 serotype indicates changes of another epidemic of DHF due to DEN1 serotype. The stresses the urgent need for implementation of measures to control the transmission of dengue infection.en_US
dc.description.affiliationDepartment of Medicine, All India Institute of Medical Sciences, New Delhi-110 029.en_US
dc.identifier.citationKurukumbi M, Wali JP, Broor S, Aggarwal P, Seth P, Handa R, Dhar L, Vajapayee M. Seroepidemiology and active surveillance of dengue fever/dengue haemorrhagic fever in Delhi. Indian Journal of Medical Sciences. 2001 Mar; 55(3): 149-56en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/67546
dc.language.isoengen_US
dc.source.urihttps://www.indianjmedsci.orgen_US
dc.subject.meshAdulten_US
dc.subject.meshDengue --epidemiologyen_US
dc.subject.meshDengue Hemorrhagic Fever --epidemiologyen_US
dc.subject.meshDeveloping Countriesen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshIndia --epidemiologyen_US
dc.subject.meshMaleen_US
dc.subject.meshPopulation Surveillanceen_US
dc.subject.meshSeroepidemiologic Studiesen_US
dc.subject.meshUrban Population --statistics & numerical dataen_US
dc.titleSeroepidemiology and active surveillance of dengue fever/dengue haemorrhagic fever in Delhi.en_US
dc.typeJournal Articleen_US
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