A Study on Actue Kidney Injury in Patients of Dengue Fever in Western Uttar Pradesh Population
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Date
2019-09
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Publisher
International Society for Contemporary Medical Research
Abstract
Introduction: Dengue fever is a systemic acute viral illnesscaused by Arbo virus from genus flavivirus highly prevalentin the tropics and subtropics, transmitted by Aedes (aegyptiand albopictus) mosquito. Pathogenesis of AKI due to dengueinclude direct action by the virus, hemodynamic instability,rhabdomyolysis, hemolysis and acute glomerular injury.Thisstudy was planned to know the incidence and severity of AKIin patients of Dengue fever.Material and methods: Our study was an observationalretrospective study, done in Subharti Medical College, Deptt.Of Medicine, Meerut between july 2017-December 2018.Medical records of 320 Dengue IgM+ patients admitted duringthis period were studied. Patients were classified into denguefever, dengue hemmorhagic fever, dengue shock syndrome.Results: Out of total 320 patients positive for dengue IgM,48 patients (15%) were found to develop AKI. Out of thetotal 48 patients developing AKI, 26 patients presented withDengue fever, 16 were with Dengue Hemmorhagic Fever and 6presented with dengue shock syndrome. Out of the 48 patientsdiagnosed with AKI, 34 patients fall under KDIGO criteria I, 10patients fall under KDIGO II, 4 patients fall under KDIGO III.Conclusion: Our study concluded that AKI is a major andserious complication,and it is the major cause of Mortality andmorbidity in dengue fever.
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Keywords
Dengue, AKI
Citation
Kumar Amit, Saini Arpit, Gupta Abhishek. A Study on Actue Kidney Injury in Patients of Dengue Fever in Western Uttar Pradesh Population. International Journal of Contemporary Medical Research . 2019 Sep; 6(9): i18-i20