The prevalence of varicella-zoster virus infection in normal healthy individuals aged above 6 months.

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dc.contributor.authorKowitdamrong, Ekasiten_US
dc.contributor.authorPancharoen, Chitsanuen_US
dc.contributor.authorThammaborvorn, Rungtipen_US
dc.contributor.authorBhattarakosol, Parvapanen_US
dc.date.accessioned2009-05-27T21:32:06Z
dc.date.available2009-05-27T21:32:06Z
dc.date.issued2005-09-21en_US
dc.descriptionChotmaihet Thangphaet.en_US
dc.description.abstractThe prevalence of varicella-zoster virus (VZV) infection was studied by determining the presence of IgG antibody to VZV (anti-VZV IgG) using ELISA method. Three hundred and fifty sera collected from Thai healthy individuals aged above 6 months (mean age +/- standard deviation = 14.9 +/- 11.4) were tested, the prevalence of VZV infection was 64.6% (225/350). All samples were randomly sampling from healthy children and blood donors who visited the hospital and clssified into 7 groups, 50 samples each, according to their age, i.e., group 1; 6 months-3 years, group 2; 4-6 years, group 3; 7-9 years, group 4; 10-14 years, group 5; 15-19 years, group 6; 20-24 years and group 7; above 25 years. The prevalence of VZV infection were 12%, 42%, 64%, 70%, 78%, 84% and 100% respectively. The mean amount of anti-VZV IgG among groups of positive VZV infection (225 samples) was 86.8 +/- 29.7 unit/ml. The mean amount of anti-VZV IgG was highest in 6 months-3 years age group (113.6 +/- 39.2 unit/ml). Significant difference of the mean amount of anti- VZV IgG was found between group 1, 3, 6 and other groups (p-value < 0.05). There was a correlation between history of varicella and the presence of anti-VZV IgG in the serum. 95.3% of individuals with positive history has already had the antibody. The important associated factors that might involve VZV infection were age, number of members in family and place of exposure to VZV infection. Other factors, such as sex and income did not show any association to VZV infection.en_US
dc.description.affiliationDepartment of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.en_US
dc.identifier.citationKowitdamrong E, Pancharoen C, Thammaborvorn R, Bhattarakosol P. The prevalence of varicella-zoster virus infection in normal healthy individuals aged above 6 months. Journal of the Medical Association of Thailand. 2005 Sep; 88 Suppl 4(): S7-11en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/44957
dc.language.isoengen_US
dc.source.urihttps://www.mat.or.th/journal/all.phpen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshChickenpox --epidemiologyen_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshFemaleen_US
dc.subject.meshHerpesvirus 3, Human --isolation & purificationen_US
dc.subject.meshHumansen_US
dc.subject.meshInfanten_US
dc.subject.meshMaleen_US
dc.subject.meshQuestionnairesen_US
dc.subject.meshSeroepidemiologic Studiesen_US
dc.subject.meshThailand --epidemiologyen_US
dc.titleThe prevalence of varicella-zoster virus infection in normal healthy individuals aged above 6 months.en_US
dc.typeJournal Articleen_US
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