Antibodies to leptospirosis in rodents from Thailand using a modified human diagnostic assay.

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dc.contributor.authorKollars, Thomas Men_US
dc.contributor.authorPhulsuksombati, Duangpornen_US
dc.contributor.authorKingnate, Darikaen_US
dc.contributor.authorPrachumsri, Jetsumonen_US
dc.contributor.authorRachphaew, Nattawanen_US
dc.contributor.authorMonkanna, Taweesaken_US
dc.contributor.authorGettayakamin, Montipen_US
dc.date.accessioned2009-05-27T18:57:48Z
dc.date.available2009-05-27T18:57:48Z
dc.date.issued2002-01-22en_US
dc.descriptionChotmaihet Thangphaet.en_US
dc.description.abstractThe number of reported cases of Leptospirosis in Thailand has grown since 1996. Identification of major reservoirs and endemic areas is essential in surveillance of Leptospira species in Thailand. To assist in the effort of surveillance, a dipstick assay for detecting Leptospira antibodies in mammals was adapted from a human diagnostic assay and tested in a field trial in Thailand. Antibodies to Leptospira were detected in 18 of 60 wild rodents. Four of 9 culture positive rodents were positive by the dipstick assay. The proportion of sera positive for antibodies by dipstick was correlated with positive culture outcome using McNemar test for correlated proportions (0.83, P> 0.05). The dipstick assay was effective in detecting antibodies to Leptospira in mammals and may be useful in resource poor areas or under circumstances where the microagglutination test (MAT) is not practical.en_US
dc.description.affiliationDepartment of Entomology, United States Army Medical Component, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.en_US
dc.identifier.citationKollars TM, Phulsuksombati D, Kingnate D, Prachumsri J, Rachphaew N, Monkanna T, Gettayakamin M. Antibodies to leptospirosis in rodents from Thailand using a modified human diagnostic assay. Journal of the Medical Association of Thailand. 2002 Jan; 85(1): 67-70en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/40198
dc.language.isoengen_US
dc.source.urihttps://www.mat.or.th/journal/all.phpen_US
dc.subject.meshAgglutination Testsen_US
dc.subject.meshAnimalsen_US
dc.subject.meshAntibodies, Bacterial --blooden_US
dc.subject.meshEndemic Diseasesen_US
dc.subject.meshHumansen_US
dc.subject.meshLeptospira --immunologyen_US
dc.subject.meshLeptospirosis --diagnosisen_US
dc.subject.meshProbabilityen_US
dc.subject.meshRodentiaen_US
dc.subject.meshSensitivity and Specificityen_US
dc.subject.meshThailand --epidemiologyen_US
dc.titleAntibodies to leptospirosis in rodents from Thailand using a modified human diagnostic assay.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
dc.typeResearch Support, U.S. Gov't, Non-P.H.S.en_US
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