Application of liquid biopsy in lung cancer management

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dc.contributor.authorSatapathy, Shraddhanjalien_US
dc.contributor.authorThirunavukkarasu, Balamuruganen_US
dc.contributor.authorJain, Deepalien_US
dc.date.accessioned2025-05-09T09:57:05Z
dc.date.available2025-05-09T09:57:05Z
dc.date.issued2024-09
dc.description.abstractCurrent advances in the understanding of the lung cancer landscape have drastically changed the approach to treating a patient with lung carcinoma. The field has progressed from analyzing single gene to using advanced techniques like next?generation sequencing and microarray technology. While a tumor tissue sample is considered the gold standard, it has several limitations. The limitations of invasive procedures, long processing periods, inaccessibility, and sample inadequacy are being addressed by sampling biofluids, termed ‘liquid biopsy,’ which offers a less invasive and more accessible way to obtain tumor?related information. Liquid biopsy has transformed the care of lung cancer patients by directly targeting somatic alterations from tumors. This article provides insights into the biology, technical aspects, limitations, and practical applications of ‘liquid biopsy,’ focusing on cell?free DNA and circulating tumor DNA in the context of lung cancer.en_US
dc.identifier.affiliationsDepartment of Pathology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, Indiaen_US
dc.identifier.affiliationsDepartment of Pathology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, Indiaen_US
dc.identifier.affiliationsDepartment of Pathology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, Indiaen_US
dc.identifier.citationSatapathy Shraddhanjali, Thirunavukkarasu Balamurugan, Jain Deepali . Application of liquid biopsy in lung cancer management. Indian Journal of Pathology & Microbiology. 2024 Sep; 67(3): 492-501en_US
dc.identifier.issn0377-4929
dc.identifier.issn0974-5130
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/245473
dc.languageenen_US
dc.publisherWolters Kluwer – Medknowen_US
dc.relation.issuenumber3en_US
dc.relation.volume67en_US
dc.source.urihttps://doi.org/10.4103/ijpm.ijpm_944_23en_US
dc.subjectcfDNAen_US
dc.subjectCTCen_US
dc.subjectctDNAen_US
dc.subjectextracellular vesicleen_US
dc.subjectfragmentosomeen_US
dc.subjectliquid biopsyen_US
dc.subjectlung adenocarcinomaen_US
dc.titleApplication of liquid biopsy in lung cancer managementen_US
dc.typeJournal Articleen_US
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