Prevalence of Drug Interactions and Potentially Inappropriate Medications Among Geriatric Patients in India.

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dc.contributor.authorYoganna, PNen_US
dc.contributor.authorSandra, Aen_US
dc.contributor.authorBachol, Ken_US
dc.contributor.authorMaheswari, Een_US
dc.contributor.authorAruna, Sree P.en_US
dc.date.accessioned2023-07-14T06:58:53Z
dc.date.available2023-07-14T06:58:53Z
dc.date.issued2022-12
dc.description.abstractAim: The study aimed to determine the prevalence of potential drug-drug interactions (PDDIs) and potentially inappropriate medications (PIMs) among geriatrics. Methods: A prospective observational study was conducted for six months in the Department of Geriatrics, M.S. Ramaiah Teaching Hospital, Bangalore. PDDIs and PIMS were analyzed using micromedex database and Beer's criteria respectively. Results: Among 395 prescriptions, 221(56%) prescriptions showed 559 pDDIs and 41(10.4%) PIMs. Almost 281(50.3%), 260(46.5%), 16(2.7%) and 2(0.3%) pDDIs were categorised as major, moderate, minor and contraindicated respectively. Almost 321(57.5%) were synergistic and 196(35.0%) were antagonistic drug interactions. Pearson correlation value (R) is 0.9957 which showed a strong positive correlation. Conclusion: This study created awareness on drug interactions among geriatrics and help the practitioners to prescribe drugs with a low risk of pDDIs. The authors suggest PIM monitoring in geriatrics to avoid adverse effects and improve patients' quality of life.en_US
dc.identifier.affiliationsDepartment of Pharmacy Practice, Faculty of Pharmacy, M. S. Ramaiah University of Applied Sciencesen_US
dc.identifier.affiliationsDepartment of Pharmacy Practice, Faculty of Pharmacy, M. S. Ramaiah University of Applied Sciencesen_US
dc.identifier.affiliationsDepartment of Geriatrics, M.S. Ramaiah Teaching Hospital Bengaluru, Karnataka 560054.en_US
dc.identifier.citationYoganna PN, Sandra A, Bachol K, Maheswari E, Aruna Sree P.. Prevalence of Drug Interactions and Potentially Inappropriate Medications Among Geriatric Patients in India.. Light House Polyclinic. 2022 Dec; 21(4): 1-5en_US
dc.identifier.issn0972-5997
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/218330
dc.languageenen_US
dc.publisherLight House Polyclinicen_US
dc.relation.issuenumber4en_US
dc.relation.volume21en_US
dc.source.urihttps://www.ojhas.org/issue84/2022-4-7.pdfen_US
dc.subjectAdverse effectsen_US
dc.subjectBeer's criteriaen_US
dc.subjectGeriatricsen_US
dc.subjectPotential Drug-Drug Interactionsen_US
dc.subjectPotentially Inappropriate Medications.en_US
dc.titlePrevalence of Drug Interactions and Potentially Inappropriate Medications Among Geriatric Patients in India.en_US
dc.typeJournal Articleen_US
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