Coinfection with epstein barr virus in north Indian patients with HIV/AIDS.

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dc.contributor.authorMujtaba, Sen_US
dc.contributor.authorVarma, Sen_US
dc.contributor.authorSehgal, Sen_US
dc.date.accessioned2005-07-10en_US
dc.date.accessioned2009-05-29T12:41:20Z
dc.date.available2005-07-10en_US
dc.date.available2009-05-29T12:41:20Z
dc.date.issued2005-07-10en_US
dc.description.abstractAcquired immunodeficiency syndrome (AIDS) has emerged as a serious health problem in India. Although tuberculosis appears to be the commonest opportunistic infection, studies pertaining to opportunistic viruses are scant In the present study co infection with EBV was evaluated in patients with AIDS using a highly sensitive polymerase chain reaction besides anti Zebra antibody assays for diagnosis of an active EBV infection in 37 patients of full-blown AIDS and 32 healthy seropositives. Thirty healthy laboratory workers were used as controls. Out of 37 patients with AIDS, 12 were positive for anti Zebra antibodies and 23 were positive for EBV by the PCR reaction. Out of the 32 seropositives, 3 were positive for anti Zebra antibodies and 4 were positive by PCR assay. The difference between seropositives and AIDS was significant (p < .05). None of the controls were positive for an active EBV infection. It is concluded that active EBV infection is an important co infection in patients with AIDS and may contribute significantly to morbidity and mortality in these patients.en_US
dc.description.affiliationDepartment of Immunopathology, Postgraduate Institute of Medical Education and Research, Chandigarh.en_US
dc.identifier.citationMujtaba S, Varma S, Sehgal S. Coinfection with epstein barr virus in north Indian patients with HIV/AIDS. Indian Journal of Pathology & Microbiology. 2005 Jul; 48(3): 349-53en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/74857
dc.language.isoengen_US
dc.source.urihttps://www.ijpmonline.orgen_US
dc.subject.meshAdulten_US
dc.subject.meshAntibodies, Viral --blooden_US
dc.subject.meshDNA-Binding Proteins --immunologyen_US
dc.subject.meshEpstein-Barr Virus Infections --complicationsen_US
dc.subject.meshFemaleen_US
dc.subject.meshHIV Infections --complicationsen_US
dc.subject.meshHIV Seropositivity --complicationsen_US
dc.subject.meshHIV-1 --isolation & purificationen_US
dc.subject.meshHerpesvirus 4, Human --geneticsen_US
dc.subject.meshHumansen_US
dc.subject.meshIncidenceen_US
dc.subject.meshIndia --epidemiologyen_US
dc.subject.meshMaleen_US
dc.subject.meshPolymerase Chain Reaction --methodsen_US
dc.subject.meshTrans-Activators --immunologyen_US
dc.subject.meshViral Proteins --immunologyen_US
dc.titleCoinfection with epstein barr virus in north Indian patients with HIV/AIDS.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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