Serological response to immunization with tetanus toxoid.

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dc.contributor.authorSetarunnahar,en_US
dc.contributor.authorHossain, Aen_US
dc.contributor.authorKhatun, Ren_US
dc.contributor.authorParveen, Sen_US
dc.contributor.authorAhmad, Zen_US
dc.contributor.authorHaleem, Aen_US
dc.contributor.authorAlam, S Ken_US
dc.date.accessioned2000-04-24en_US
dc.date.accessioned2009-05-27T03:47:04Z
dc.date.available2000-04-24en_US
dc.date.available2009-05-27T03:47:04Z
dc.date.issued2000-04-24en_US
dc.descriptionBangladesh Medical Research Council Bulletin.en_US
dc.description.abstractA total of two hundred women were immunized with tetanus toxoid vaccine. Two batches of toxoid prepared at the Institute of Public Health (IPH), Dhaka and one batch of imported vaccines, were being used by the EPI in Bangladesh for immunization. Each hundred women were immunized by IPH and imported vaccine. Two human doses were given in one month interval. Blood samples from all the study subjects were collected on the day of 1st dose and one month after second dose. Both the preimmunized sera and the sera after vaccination were tested to determine the antibody titre against tetanus toxoid by the haemagglutination method. The preimmunized sera showed the presence of protective antibody in 50(25%) subjects who had the history of previous immunization. Including these initial antitoxin positive cases the seroconversions found among 95% and 96% of the study population respectively after immunization with IPH and imported toxoids, which were 93.05% and 94.87% when these 50 subjects were excluded. No significant difference (p = 1.0) was observed between the immunity of the subjects after receiving IPH and imported vaccine. Antibody titre of initial tetanus-antitoxin positive cases raised eight folds after getting more doses. The result gave fair indication of the antigenicity of all the toxoids used in the study.en_US
dc.description.affiliationDPT Vaccine Laboratory, Institute of Public Health, Mohakhali, Dhaka.en_US
dc.identifier.citationSetarunnahar , Hossain A, Khatun R, Parveen S, Ahmad Z, Haleem A, Alam SK. Serological response to immunization with tetanus toxoid. Bangladesh Medical Research Council Bulletin. 2000 Apr; 26(1): 15-22en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/268
dc.language.isoengen_US
dc.source.urihttps://www.banglajol.info/index.php/BMRCB/indexen_US
dc.subject.meshAntigens, Bacterial --blooden_US
dc.subject.meshClostridium tetani --immunologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshFollow-Up Studiesen_US
dc.subject.meshHemagglutination Testsen_US
dc.subject.meshHumansen_US
dc.subject.meshImmunizationen_US
dc.subject.meshTetanus Toxoid --chemical synthesisen_US
dc.subject.meshVaccinationen_US
dc.titleSerological response to immunization with tetanus toxoid.en_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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