Association between Serum 25 (OH) Vitamin D level and Thyroiditis in Western Saudi Arabian Population

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dc.contributor.authorFarag, Naglaa Men_US
dc.contributor.authorMansour, Samaren_US
dc.contributor.authorMohammad, Walaa Hosnyen_US
dc.contributor.authorZahrani, Mubarak Bakhit Alen_US
dc.date.accessioned2020-01-02T06:12:17Z
dc.date.available2020-01-02T06:12:17Z
dc.date.issued2019-01
dc.description.abstractThe association of low vitamin D status with Autoimmune Thyroid Disease (AITD), which includes Hashimoto’s Thyroiditis (HT), is controversial. (HT) is a chronic autoimmune thyroid disease caused by an interaction between genetic factors and environmental conditions, both of which are yet to be fully understood. The management of HT depends on its clinical manifestations, commonly including diffuse or nodular goiter with euthyroidism, subclinical hypothyroidism and permanent hypothyroidism. The aim of this study was to investigate mainly the correlation between vitamin D deficiency and HT. Methods: This study was carried out in tertiary hospitals, included patients who visited the hospital for thyroid evaluation or follow-up. Results: A total of 310 subjects were included, of whom 84 participants were healthy, and 226 patients with hypothyroid disease, 119 subjects were diagnosed as having HT (AITD), 107 Non-AITD. Conclusion: The prevalence of vitamin D deficiency was significantly higher in HT group than in non AITD (48.9 % vs. 37.4 %, p=0.013). Among HT cases, patients with overt hypothyroidism had a significantly higher prevalence of vitamin D insufficiency than HT with euthyroidism, subclinical hypothyroidism (60.4% vs. 44.1%, 29.7%, respectively, p 0.009, 0.017, 0.026). Conclusion: Considering current evidence, presented in this study, screening for vitamin D deficiency and careful vitamin D supplementation, when required, may be recommended for patients with HT.en_US
dc.identifier.affiliationsClinical Pathology Department, Faculty of Medicine, Minia University, Minia, Egypt.en_US
dc.identifier.affiliationsClinical Pathology Department, South Egypt Cancer Institute, Assiut University, Assiut, Egypt.en_US
dc.identifier.affiliationsInternal Medicine Departement, Faculty of Medicine, Assuit University, Egypt.en_US
dc.identifier.affiliationsInternal Medicine and Pathology Departement, Faculty of Medicine, MBBS, FRCPA, FRACP, Jeddah, KSA.en_US
dc.identifier.citationFarag Naglaa M, Mansour Samar, Mohammad Walaa Hosny, Zahrani Mubarak Bakhit Al. Association between Serum 25 (OH) Vitamin D level and Thyroiditis in Western Saudi Arabian Population. Annals of International medical and Dental Research. 2019 Jan; 5(1): 16-21en_US
dc.identifier.issn2395-2822
dc.identifier.issn2395-2814
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/189341
dc.languageenen_US
dc.publisherSociety for Health Care & Research Developmenten_US
dc.relation.issuenumber1en_US
dc.relation.volume5en_US
dc.source.urihttps://doi.org/10.21276/aimdr.2019.5.1.PT4en_US
dc.subjectAutoimmune Thyroid Diseaseen_US
dc.subjectHashimoto’s Thyroiditisen_US
dc.subject25-Hydroxyvitamin D and Thyroid Peroxidase Antibodiesen_US
dc.titleAssociation between Serum 25 (OH) Vitamin D level and Thyroiditis in Western Saudi Arabian Populationen_US
dc.typeJournal Articleen_US
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