Management of intracranial hypertension.

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dc.contributor.authorSinghi, Sunit C
dc.contributor.authorTiwari, Lokesh
dc.date.accessioned2012-10-16T09:03:40Z
dc.date.available2012-10-16T09:03:40Z
dc.date.issued2009-05
dc.description.abstractRaised intracranial pressure (ICP) is a life threatening condition that is common to many neurological and non-neurological illnesses. Unless recognized and treated early it may cause secondary brain injury due to reduced cerebral perfusion pressure (CPP), and progress to brain herniation and death. Management of raised ICP includes care of airway, ventilation and oxygenation, adequate sedation and analgesia, neutral neck position, head end elevation by 200 -300, and short-term hyperventilation (to achieve PCO2 32- 35 mm Hg) and hyperosmolar therapy (mannitol or hypertonic saline) in critically raised ICP. Barbiturate coma, moderate hypothermia and surgical decompression may be helpful in refractory cases. Therapies aimed directly at keeping ICP <20 mmHg have resulted in improved survival and neurological outcome. Emerging evidence suggests that cerebral perfusion pressure targeted therapy may offer better outcome than ICP targeted therapies.en_US
dc.identifier.citationSinghi Sunit C, Tiwari Lokesh. Management of intracranial hypertension. Indian Journal of Pediatrics. 2009 May; 76(5): 519-529.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/142200
dc.language.isoenen_US
dc.source.urihttps://medind.nic.in/icb/t09/i5/icbt09i5p519.pdfen_US
dc.subjectIntracranial pressureen_US
dc.subjectChildrenen_US
dc.subjectTraumatic brain injuryen_US
dc.subjectCerebral perfusion pressureen_US
dc.subjectHyperosmolar therapyen_US
dc.subject.meshBarbiturates --therapeutic use
dc.subject.meshCause of Death
dc.subject.meshChild, Preschool
dc.subject.meshCombined Modality Therapy
dc.subject.meshConscious Sedation --methods
dc.subject.meshCritical Illness --therapy
dc.subject.meshEarly Diagnosis
dc.subject.meshEmergency Treatment
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshIndia
dc.subject.meshInfant
dc.subject.meshInfant, Newborn
dc.subject.meshIntensive Care Units, Pediatric
dc.subject.meshIntracranial Hypertension --diagnosis
dc.subject.meshIntracranial Hypertension --mortality
dc.subject.meshIntracranial Hypertension --therapy
dc.subject.meshIntracranial Pressure
dc.subject.meshMale
dc.subject.meshMannitol --therapeutic use
dc.subject.meshPrognosis
dc.subject.meshRespiration, Artificial
dc.subject.meshRisk Assessment
dc.subject.meshSaline Solution, Hypertonic --therapeutic use
dc.subject.meshSurvival Analysis
dc.titleManagement of intracranial hypertension.en_US
dc.typeArticleen_US
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