L-carnitine administration in coronary artery disease and cardiomyopathy.

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dc.contributor.authorSingh, R Ben_US
dc.contributor.authorAslam, Men_US
dc.date.accessioned1998-09-07en_US
dc.date.accessioned2009-05-31T02:32:49Z
dc.date.available1998-09-07en_US
dc.date.available2009-05-31T02:32:49Z
dc.date.issued1998-09-07en_US
dc.description.abstractMyocardial ischaemia may be defined as a deficiency in cardiac energy supply relative to energy demand. In coronary artery disease (CAD), oxygen supply is limited due to coronary obstruction so energy production is not enough to meet the energy demands for work. Several reports involving about 2500 patients of CAD where carnitine was administered for upto 1 year indicate some beneficial effects. There is reduction in ischaemia showing reduced ST-segment depression and angina, greater effort tolerance and decreased need of cardiac drugs. Carnitine can cause overall improvement in cardiac performance in patients with CAD as well as in cardiomyopathy. More studies are necessary to demonstrate where carnitine can scavenge free radicals apart from its beneficial effect on fatty acid metabolism. Side effects of carnitine are mild nausea and vomiting and dose upto 2 g/day in 3 divided doses may not have any side effects. Intravenous L-carnitine acts rapidly and has no side effects.en_US
dc.description.affiliationNKP Salve Institute of Medical Sciences, Nagpur.en_US
dc.identifier.citationSingh RB, Aslam M. L-carnitine administration in coronary artery disease and cardiomyopathy. Journal of the Association of Physicians of India. 1998 Sep; 46(9): 801-5en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/93135
dc.language.isoengen_US
dc.source.urihttps://www.japi.orgen_US
dc.subject.meshCarnitine --deficiencyen_US
dc.subject.meshCoronary Disease --physiopathologyen_US
dc.subject.meshDietary Supplementsen_US
dc.subject.meshHeart --drug effectsen_US
dc.subject.meshHumansen_US
dc.subject.meshMyocardial Ischemia --physiopathologyen_US
dc.titleL-carnitine administration in coronary artery disease and cardiomyopathy.en_US
dc.typeJournal Articleen_US
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