Role of 0.01% atropine in high myopic children of Moradabad, India (RAMCOM Study)

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dc.contributor.authorAgarwal, Pradeepen_US
dc.contributor.authorKhurana, Ashien_US
dc.contributor.authorMaan, Veenuen_US
dc.contributor.authorSutar, Samiren_US
dc.contributor.authorChauhan, Lokeshen_US
dc.date.accessioned2023-08-25T06:35:32Z
dc.date.available2023-08-25T06:35:32Z
dc.date.issued2022-12
dc.description.abstractPurpose: Low?concentration atropine is an emerging therapy for myopia progression, but its efficacy remains uncertain among high myopic children. This study aimed to evaluate the efficacy and safety of low?concentration atropine eye drop (0.01%) in high myopic children. Methods: A non?randomized, parallel?group, longitudinal interventional cohort study. Myopic children were divided into two groups: (1) the intervention arm of children who received one drop of topical 0.01% atropine once a day at bedtime and (2) the control arm, in which enrolled children who were on observation only. Repeated measurements of spherical equivalent refractive errors (SERs) were performed at baseline and 1 and 2 years after treatment. Results: A total of 37 eyes were enrolled in the intervention arm (allocated to 0.01% atropine at year 1 follow?up) and 23 eyes in the control arm. After 1 year of 0.01% atropine therapy, the myopia progression was 0.15 ± 0.9 D in the intervention group versus 1.1 ± 1 D in the control group (P = 0.001). Similarly, after 2 years of treatment, the myopia progression was 0.3 ± 1.1 D in the intervention group versus 1.4 ± 1.1 D in the control group (P ? 0.001). Conclusion: Compared to no treatment, 0.01% atropine treatment had shown better effect on myopia progression in high myopic childrenen_US
dc.identifier.affiliationsDepartments of Pediatric Ophthalmology, Strabismus and Neuro-Ophthalmology, CL Gupta Eye Institute, Moradabad, Uttar Pradesh, Indiaen_US
dc.identifier.affiliationsCornea and Anterior Segment, CL Gupta Eye Institute, Moradabad, Uttar Pradesh, Indiaen_US
dc.identifier.affiliationsOptometry and Visual Sciences, CL Gupta Eye Institute, Moradabad, Uttar Pradesh, Indiaen_US
dc.identifier.affiliationsClinical and Public Health Research, CL Gupta Eye Institute, Moradabad, Uttar Pradesh, Indiaen_US
dc.identifier.citationAgarwal Pradeep, Khurana Ashi, Maan Veenu, Sutar Samir, Chauhan Lokesh. Role of 0.01% atropine in high myopic children of Moradabad, India (RAMCOM Study). Indian Journal of Ophthalmology. 2022 Dec; 70(12): 4400-4404en_US
dc.identifier.issn1998-3689
dc.identifier.issn0301-4738
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/224755
dc.languageenen_US
dc.publisherAll India Ophthalmological Societyen_US
dc.relation.issuenumber12en_US
dc.relation.volume70en_US
dc.source.urihttps://doi.org/10.4103/ijo.IJO_679_22en_US
dc.subject0.01% atropineen_US
dc.subjectefficacyen_US
dc.subjecthigh myopiaen_US
dc.subjectmyopia progressionen_US
dc.subjectsafetyen_US
dc.titleRole of 0.01% atropine in high myopic children of Moradabad, India (RAMCOM Study)en_US
dc.typeJournal Articleen_US
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