Human brucellosis: review of an under-diagnosed animal transmitted disease.

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dc.contributor.authorThakur, S Den_US
dc.contributor.authorKumar, Ren_US
dc.contributor.authorThapliyal, D Cen_US
dc.date.accessioned2002-12-09en_US
dc.date.accessioned2009-06-01T18:02:51Z
dc.date.available2002-12-09en_US
dc.date.available2009-06-01T18:02:51Z
dc.date.issued2002-12-09en_US
dc.description94 references.en_US
dc.description.abstractHuman brucellosis is an important animal transmitted disease of man. Although, the cases have been recorded all over the world, the prevalence is higher in developing countries. Lack of sufficient knowledge about the disease among the physicians, its under-diagnosis or misdiagnosis and absence of effective prevention and management strategies are attributed to the widespread of the disease. Increase in the occurrence of animal brucellosis has also resulted indirectly in an increase in the prevalence of human infection. Absence of characteristic clinical symptoms, chronic nature of the infection and difficulty in isolation of the causal agent from the patients make the diagnosis of the disease more difficult. The serological tests employed for diagnosing human brucellosis vary in terms of their sensitivity and specificity. Therefore, a combination of serological tests is desirable. Currently no vaccine is available against human brucellosis, which could check the spread of the disease effectively. It is suggested that clinicians investigate the cases of pyrexia of unknown origin (PUO) for brucellosis. It is desirable that specimens from cases of tuberculosis, typhoid, rheumatoid arthritis, urogenital infections, kala-azar, cirrhosis, bacterial endocarditis, leukemia and filariasis should also be screened for brucellosis in man. The cases of meningitis of unestablished etiology as the cases of human brucellosis are often misdiagnosed as cases of typhoid or tuberculosis.en_US
dc.description.affiliationCollege of Veterinary Sciences, G.B.P.U.A. and T., Pantnagar, Uttaranchal.en_US
dc.identifier.citationThakur SD, Kumar R, Thapliyal DC. Human brucellosis: review of an under-diagnosed animal transmitted disease. Journal of Communicable Diseases. 2002 Dec; 34(4): 287-301en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/111940
dc.language.isoengen_US
dc.subject.meshAnimalsen_US
dc.subject.meshAnti-Bacterial Agents --therapeutic useen_US
dc.subject.meshBrucella --classificationen_US
dc.subject.meshBrucellosis --diagnosisen_US
dc.subject.meshDiagnostic Errorsen_US
dc.subject.meshEnzyme-Linked Immunosorbent Assayen_US
dc.subject.meshHumansen_US
dc.subject.meshPrevalenceen_US
dc.titleHuman brucellosis: review of an under-diagnosed animal transmitted disease.en_US
dc.typeJournal Articleen_US
dc.typeReviewen_US
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