Lymphocyte transformation in lepromatous leprosy: a study of the influence of disease activity and symptom duration.

Simple item page
dc.contributor.authorBrown, A Een_US
dc.contributor.authorVithayasai, Ven_US
dc.contributor.authorScollard, D Men_US
dc.contributor.authorNelson, K Een_US
dc.contributor.authorMoses, Ven_US
dc.contributor.authorSchauf, Ven_US
dc.contributor.authorMakonkawkeyoon, Sen_US
dc.date.accessioned2009-05-27T15:41:05Z
dc.date.available2009-05-27T15:41:05Z
dc.date.issued1986-03-01en_US
dc.descriptionThe Southeast Asian Journal of Tropical Medicine and Public Health.en_US
dc.description.abstractThe lymphocyte hyporesponsiveness to M. leprae of patients with active lepromatous leprosy has been well described. This immune defect is less well understood in terms of its time of origin, possible reversibility and specificity. To further examine the persistence and specificity of this abnormality, lymphocyte transformation tests of 93 leprosy patients to lepromin, BCG and PHA were studied. Among lepromatous patients, a decreased response to M. leprae was seen, whether the disease was active or inactive. Decreased responses to BCG were found in lepromatous patients with active disease, but not in those with inactive disease. The duration of patient symptoms was not associated with differences in LTT responses among the active lepromatous patients.en_US
dc.identifier.citationBrown AE, Vithayasai V, Scollard DM, Nelson KE, Moses V, Schauf V, Makonkawkeyoon S. Lymphocyte transformation in lepromatous leprosy: a study of the influence of disease activity and symptom duration. The Southeast Asian Journal of Tropical Medicine and Public Health. 1986 Mar; 17(1): 104-10en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/33403
dc.language.isoengen_US
dc.source.urihttps://www.tm.mahidol.ac.th/seameo/publication.htmen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshBCG Vaccine --pharmacologyen_US
dc.subject.meshHumansen_US
dc.subject.meshLeprominen_US
dc.subject.meshLeprosy --immunologyen_US
dc.subject.meshLymphocyte Activationen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPhytohemagglutinins --pharmacologyen_US
dc.titleLymphocyte transformation in lepromatous leprosy: a study of the influence of disease activity and symptom duration.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
dc.typeResearch Support, U.S. Gov't, P.H.S.en_US
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description:
Download
Collections
Southeast Asian Journal of Tropical Medicine and Public Health