Association of ompU gene in Vibrio cholerae from patients and environment with bile resistance.

dc.contributor.authorChomvarin, Chariyaen_US
dc.contributor.authorJumroenjit, Warinen_US
dc.contributor.authorChaicumpar, Kunyaluken_US
dc.contributor.authorNamwat, Wisesen_US
dc.date.accessioned2009-05-27T16:11:23Z
dc.date.available2009-05-27T16:11:23Z
dc.date.issued2008-09-09en_US
dc.descriptionThe Southeast Asian Journal of Tropical Medicine and Public Health.en_US
dc.description.abstractThe objective of this study was to determine whether Vibrio cholerae, possessing ompU isolated from patients and the environment, conferred bile resistance and whether other virulence genes were also related to bile resistance. Fifty-two V cholerae O1 and non-O1 isolates were examined by PCR for the presence of the virulence-associated and regulatory genes, ctxA, tcpA, zot, ace, ompU, toxR, hlyA and stn/sto. V. cholerae possessing ompU resistant to equal or greater than 10% sodium deoxycholate were found in 93% of isolates but only in 9% of V. cholerae isolates not possessing ompU. The effects of other virulence genes on bile resistance could not be ascertained in this study. Thus V cholerae non-O1 with ompU and possibly other virulence genes isolated from the environment have the potential of affecting public health.en_US
dc.description.affiliationDepartment of Microbiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand. chariya@kku.ac.then_US
dc.identifier.citationChomvarin C, Jumroenjit W, Chaicumpar K, Namwat W. Association of ompU gene in Vibrio cholerae from patients and environment with bile resistance. The Southeast Asian Journal of Tropical Medicine and Public Health. 2008 Sep; 39(5): 876-81en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/34628
dc.language.isoengen_US
dc.source.urihttps://www.tm.mahidol.ac.th/seameo/2008_39_5/16-4300.pdfen_US
dc.subject.meshAdhesins, Bacterial --geneticsen_US
dc.subject.meshBacteriological Techniquesen_US
dc.subject.meshBile --physiologyen_US
dc.subject.meshDeoxycholic Acid --pharmacologyen_US
dc.subject.meshDrug Resistance, Bacterial --geneticsen_US
dc.subject.meshEnvironmental Monitoringen_US
dc.subject.meshGenes, Bacterialen_US
dc.subject.meshGenes, Regulatoren_US
dc.subject.meshHumansen_US
dc.subject.meshPolymerase Chain Reactionen_US
dc.subject.meshThailanden_US
dc.subject.meshVibrio cholerae O1 --geneticsen_US
dc.subject.meshVibrio cholerae non-O1 --geneticsen_US
dc.subject.meshVirulenceen_US
dc.subject.meshWater Microbiologyen_US
dc.titleAssociation of ompU gene in Vibrio cholerae from patients and environment with bile resistance.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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