Langerhans cell histiocytosis of thyroid: Case report with review of literature

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dc.contributor.authorYadav, Subhash C.en_US
dc.contributor.authorBal, Munitaen_US
dc.contributor.authorPatil, Asawarien_US
dc.date.accessioned2023-08-09T06:04:06Z
dc.date.available2023-08-09T06:04:06Z
dc.date.issued2022-03
dc.description.abstractLangerhans cell histiocytosis (LCH) is a rare monoclonal disease of antigen presenting cells. Involvement of thyroid gland by LCH is exceedingly rare. Herein, we present a case of LCH involving the thyroid in a 38-year-old woman. Our patient presented clinically as a case of primary thyroid neoplasm. Presence of elongated, epithelioid neoplastic cells with grooved nuclei along with presence of background eosinophils were seen on fine-needle aspiration cytology (FNAC) and histopathology. Positive staining for CD1a and S100 immunohistochemistry confirmed the diagnosis of LCH. Patient was given combination chemotherapy and has responded well to the same without any complaints for last 6 months. With this report, our goal is to expand awareness of this rare tumor in the thyroid. Consideration at the time of FNAC and its correct diagnosis on subsequent excision is imperative for patient management.thyroiden_US
dc.identifier.affiliationsDepartment of Surgical Pathology, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, Maharashtra, Indiaen_US
dc.identifier.citationYadav Subhash C., Bal Munita, Patil Asawari. Langerhans cell histiocytosis of thyroid: Case report with review of literature. Indian Journal of Cancer . 2022 Mar; 59(1): 115-118en_US
dc.identifier.issn0019-509X
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/221660
dc.languageenen_US
dc.publisherWolters Kluwer - Medknowen_US
dc.relation.issuenumber1en_US
dc.relation.volume59en_US
dc.source.urihttps://doi.org/10.4103/ijc.IJC_608_20en_US
dc.subjectCytologyen_US
dc.subjecthistopathologyen_US
dc.subjectimmunohistochemistryen_US
dc.subjectLangerhans cell histiocytosisen_US
dc.subjectthyroiden_US
dc.titleLangerhans cell histiocytosis of thyroid: Case report with review of literatureen_US
dc.typeJournal Articleen_US
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