125I brachytherapy seeds implantation for an inoperable large retroperitoneal leiomyosarcoma

Simple item page
dc.contributor.authorDi, Xueminen_US
dc.contributor.authorLiang, Yansongen_US
dc.contributor.authorYu, Huiminen_US
dc.contributor.authorZhao, Jinxinen_US
dc.contributor.authorWang, Zeyangen_US
dc.contributor.authorZhao, Jingen_US
dc.contributor.authorSui, Aixiaen_US
dc.contributor.authorZhang, Hongtaoen_US
dc.contributor.authorWang, Juanen_US
dc.date.accessioned2020-11-18T10:08:19Z
dc.date.available2020-11-18T10:08:19Z
dc.date.issued2020-05
dc.description.abstractRetroperitoneal leiomyosarcoma is relatively uncommon. Leiomyosarcoma has accounted for about 5%-10% of soft-tissue sarcoma, and 1/2–2/3 of the primary lesions were retroperitoneal, with a cumulative 5-year survival rate of only 35%.Leiomyosarcoma is one kind of soft-tissue sarcoma with the lowest survival rates due to the invasive growth, difficult treatment, and poor prognosis.The present study reported a case of a 78-year-old male diagnosed as left retroperitoneal leiomyosarcoma, who had received three operations. Computed tomography (CT) demonstrated a mass of approximately 12.9 cm × 6.9 cm × 6.6 cm in his retroperitoneal region. The Eastern cooperative oncology group and numerical rating scale scores of pain were 1 and 5, respectively. Multiple treatment strategies were administered, including the application of drainage and125I seed implantation. A total of 90125I seeds were implanted into the tumor through repetitious operations, with 30 seeds each time. Treatment planning system was involved to calculate the source distribution.125I seeds with the activity of 0.5 mCi were implanted under the guidance of CT, and dosimetric verification was performed after the operation. D90 (90% minimum prescription dose received by target volume) was 40 Gy. Follow-up was performed after 6 months, and complete response was achieved in the local lesions. However, there was no evidence-based treatment currently and the majority of our knowledge was based on results from case reports, thus further studies would be requireden_US
dc.identifier.affiliationsDepartment of Oncology, The Hebei General Hospital, Shijiazhuang, Hebei Province, Chinaen_US
dc.identifier.citationDi Xuemin, Liang Yansong, Yu Huimin, Zhao Jinxin, Wang Zeyang, Zhao Jing, Sui Aixia, Zhang Hongtao, Wang Juan. 125I brachytherapy seeds implantation for an inoperable large retroperitoneal leiomyosarcoma. Journal of Cancer Research and Therapeutics. 2020 May; 16(2): 397en_US
dc.identifier.issn0973-1482
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/213831
dc.languageenen_US
dc.publisherWolters Kluwer India Pvt. Ltd.en_US
dc.relation.issuenumber2en_US
dc.relation.volume16en_US
dc.source.urihttps://dx.doi.org//10.4103/jcrt.JCRT_66_18en_US
dc.subject125 I seeden_US
dc.subjectbrachytherapyen_US
dc.subjectinoperableen_US
dc.subjectretroperitoneal leiomyosarcomaen_US
dc.title125I brachytherapy seeds implantation for an inoperable large retroperitoneal leiomyosarcomaen_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
ijcrt2020v16n2p397.pdf
Size:
1003.07 KB
Format:
Adobe Portable Document Format
Download
Collections
Journal of Cancer Research and Therapeutics