Retrospective study of clinical profile and management of patients with swine flu at tertiary care hospital

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dc.contributor.authorJethani, Varunaen_US
dc.contributor.authorKhanduri, Rakheeen_US
dc.contributor.authorKhanduri, Sushanten_US
dc.contributor.authorTaneja, Nehaen_US
dc.contributor.authorAggarwal, Ankiten_US
dc.date.accessioned2020-11-18T09:57:30Z
dc.date.available2020-11-18T09:57:30Z
dc.date.issued2019-01
dc.description.abstractBackground: The first isolation of a swine influenza virus from a human occurred in 1974. There are no unique clinical features that distinguish swine influenza in humans from typical influenza. Thus, clinical course and management were recorded as per a planned pro forma and analysed. This type of study has not been done previously in Himalayan region.Methods: Retrospective observational study done in a group of patients diagnosed with swine flu admitted in department of pulmonary medicine at the tertiary care hospital from November 2016 to July 2017.Results: Out of 30 patients, 53.3% were male, mean age was 48.8±17.7, history of travel or contact to infected person was only 13.3%. Most common symptom recorded was fever (83.3%), followed by dyspnoea, cough, throat pain. Most common co-morbidity was diabetes and presence were significantly associated with admission in an ICU (P<0.05). Bilateral lung infiltrate seen in 53.3% on chest X-ray. Organ involved other than respiratory were renal followed by liver involvement. 40% of patients received corticosteroid for an average of 6days, mostly given in patients with sepsis, septic shock, multi organ involvement. Out of 40%, 16.6% patient expired, 6.6% left against medical advice and 16.6% were discharged, corticosteroid doesn’t help in reducing mortality.Conclusions: A multivariate model to identify independent predictors associated with mortality in swine flu were the use of vasopressor, respiratory failure, requirement of mechanical ventilation and number of organ failure. Use of corticosteroid is controversial.en_US
dc.identifier.affiliationsDepartment of Pulmonary Medicine, Himalayan Institute of Medical Science, Jolly Grant, Dehradun, Uttarakhand, Indiaen_US
dc.identifier.affiliationsDepartment of Community Medicine, North DMC Medical College, Hindu Rao Hospital, Delhi, Indiaen_US
dc.identifier.citationJethani Varuna, Khanduri Rakhee, Khanduri Sushant, Taneja Neha, Aggarwal Ankit. Retrospective study of clinical profile and management of patients with swine flu at tertiary care hospital. International Journal of Research in Medical Sciences. 2019 Jan; 7(1): 251-254en_US
dc.identifier.issn2320-6071
dc.identifier.issn2320-6012
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/211103
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber1en_US
dc.relation.volume7en_US
dc.source.urihttps://dx.doi.org/10.18203/2320-6012.ijrms20185390en_US
dc.subjectCorticosteroidsen_US
dc.subjectMortalityen_US
dc.subjectSwine fluen_US
dc.titleRetrospective study of clinical profile and management of patients with swine flu at tertiary care hospitalen_US
dc.typeJournal Articleen_US
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