Role of PPI and importance of anti-reflux agents in the treatment of NERD
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Date
2022-11
Authors
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Publisher
Indian Medical Association
Abstract
Background: Esomeprazole, an S-isomer of omeprazole, is a much more potent acid inhibitor than most other currently available PPIs and gives excellent results. Therefore, it is a first-line drug for acid-related diseases like NonErosive Reflux Disease (NERD). Yet, patients demand faster onset and response. Aim : To establish the role of esomeprazole and the importance of anti-reflux agents like a combination of two antacids (calcium carbonate and sodium bicarbonate) and alginate in treating NERD. Conclusion: Esomeprazole therapy shows potential efficacy in the continuous maintenance treatment of the NERD. However, it is suggested that to improve the efficiency of esomeprazole for the treatment of NERD; we can supplement the drug with antacids (sodium bicarbonate and calcium carbonate) and alginates.
Description
Keywords
Esomeprazole, PPI, Antacids, Non-erosive reflux disease, Alginates
Citation
Biswas K D, Purohit Deepak. Role of PPI and importance of anti-reflux agents in the treatment of NERD. Journal of The Indian Medical Association. 2022 Nov; 120(11): 69-70