Bronchiectasis in patients with chronic obstructive pulmonary disease in a tertiary care center in North-East India

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dc.contributor.authorSangtam, Noklangkumlaen_US
dc.contributor.authorHaorongbam, Sunandaen_US
dc.contributor.authorSilpa, Kshetrimayumen_US
dc.contributor.authorSingh, Yumnam Priyabartaen_US
dc.date.accessioned2020-04-09T07:43:57Z
dc.date.available2020-04-09T07:43:57Z
dc.date.issued2020-04
dc.description.abstractBackground: Bronchiectasis is common in patients with Chronic Obstructive Pulmonary Disease (COPD). COPD with bronchiectasis has been considered a phenotype with worse lung function and more severe exacerbations. There is scarce literature on the characteristics and optimal management of such patients.Methods:Patients with COPD reporting within the one-year study period were subjected to High Resolution Computed Tomography (HRCT) scan of the thorax. Sputum was sent for Gram-stain and culture/sensitivity for patients found to have bronchiectasis. Bronchiectasis Severity Index (BSI) was calculated using the online BSI calculator. Association between presence of bronchiectasis and gender, lung function and frequency of exacerbations was statistically analysed.Results: Total 62 patients with COPD were enrolled. Bronchiectasis was present in 11 (17.7%) patients. The most common bacterial isolate from sputum of patients with bronchiectasis was Haemophilus influenza (54.54%). The prevalence of bronchiectasis was more in females (19.45% compared to 15.4% in males), but this association was not found to be statistically significant(p=0.748). Forced Expiratory volume in 1st second (FEV1) was found to be significantly lower in patients with bronchiectasis (p<0.05). There was increased frequency of exacerbations among patients with bronchiectasis. This association was however not found to be statistically significant (p=0.765), 1 (9.1%) patient had low BSI score (0-4), 3 (27.3%) patients had intermediate BSI score (5-8) and 7 (63.3%) patients had high BSI score (?9).Conclusions:The presence of bronchiectasis in COPD is a phenotype associated with a poor clinical course. The characteristics of this co-existence are largely unknown. More studies are required to properly characterize and manage patients with this coexistence.en_US
dc.identifier.affiliationsConsultant Physician, City Hospital, Kamptee, Nagpur, Maharashtra, Indiaen_US
dc.identifier.affiliationsConsultant Anaesthesiologist, City Hospital, Kamptee, Nagpur, Maharashtra, Indiaen_US
dc.identifier.citationSangtam Noklangkumla, Haorongbam Sunanda, Silpa Kshetrimayum, Singh Yumnam Priyabarta. Bronchiectasis in patients with chronic obstructive pulmonary disease in a tertiary care center in North-East India. International Journal of Advances in Medicine. 2020 Apr; 7(4): 656-660en_US
dc.identifier.issn2349-3925
dc.identifier.issn2349-3933
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/194656
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber4en_US
dc.relation.volume7en_US
dc.source.urihttps://dx.doi.org/10.18203/2349-3933.ijam20201117en_US
dc.subjectBronchiectasisen_US
dc.subjectChronic obstructive pulmonary diseaseen_US
dc.subjectExacerbationsen_US
dc.subjectPhenotypeen_US
dc.titleBronchiectasis in patients with chronic obstructive pulmonary disease in a tertiary care center in North-East Indiaen_US
dc.typeJournal Articleen_US
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