The future implications and indications of anti-vascular endothelial growth factor therapy in ophthalmic practice.

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dc.contributor.authorHussain, Nazimulen_US
dc.contributor.authorGhanekar, Yashodaen_US
dc.contributor.authorKaur, Inderjeeten_US
dc.date.accessioned2007-11-24en_US
dc.date.accessioned2009-05-29T08:45:33Z
dc.date.available2007-11-24en_US
dc.date.available2009-05-29T08:45:33Z
dc.date.issued2007-11-24en_US
dc.description56 references.en_US
dc.description.abstractIn the last few years anti-vascular endothelial growth factor (VEGF) therapy has changed the paradigm in the treatment of neovascular age-related macular degeneration (ARMD). Besides, its potential use in the treatment of diabetic retinopathy and other possible proliferative vascular disorders has also shown promise. Clinical trial results have shown tremendous beneficial effect of ranibizumab in ARMD. Off-label use of bevacizumab has also shown similar benefit but long-term and clinical trial results do not exist. Some of the potential questions in the use of anti-VEGF are recurring cost, possible long-term effect on physiological function of VEGF and determination of endpoint of treatment. Overall, the use of anti-VEGF therapy in ocular angiogenesis has proven to be beneficial at least now.en_US
dc.description.affiliationSmt. Kanuri Santhamma Retina Vitreous Centre, L.V. Prasad Eye Institute, Hyderabad, Andhra Pradesh, India. nazimul@lvpei.orgen_US
dc.identifier.citationHussain N, Ghanekar Y, Kaur I. The future implications and indications of anti-vascular endothelial growth factor therapy in ophthalmic practice. Indian Journal of Ophthalmology. 2007 Nov-Dec; 55(6): 445-50en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/70838
dc.language.isoengen_US
dc.source.urihttps://www.ijo.inen_US
dc.source.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2635990/en_US
dc.subject.meshAngiogenesis Inhibitors --therapeutic useen_US
dc.subject.meshClinical Trials as Topic --trendsen_US
dc.subject.meshHumansen_US
dc.subject.meshMacular Degeneration --drug therapyen_US
dc.subject.meshVascular Endothelial Growth Factor A --antagonists & inhibitorsen_US
dc.titleThe future implications and indications of anti-vascular endothelial growth factor therapy in ophthalmic practice.en_US
dc.typeJournal Articleen_US
dc.typeReviewen_US
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