Studies on Brugia pahangi in inbred hamsters. 1. Susceptibility of inbred GN and APG hamsters.

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dc.contributor.authorShigeno, Sen_US
dc.contributor.authorYamashita, Sen_US
dc.contributor.authorTakahashi, Hen_US
dc.contributor.authorKimura, Een_US
dc.contributor.authorAoki, Yen_US
dc.contributor.authorNakajima, Yen_US
dc.date.accessioned2009-05-27T15:10:49Z
dc.date.available2009-05-27T15:10:49Z
dc.date.issued1983-09-01en_US
dc.descriptionThe Southeast Asian Journal of Tropical Medicine and Public Health.en_US
dc.description.abstractThe susceptibility of inbred GN and APG hamsters to Brugia pahangi infection was studied. Male GN hamsters infected subcutaneously with 100 infective larvae showed 100% patency with the average prepatent period of 69 days. The average microfilarial density was 148/40 c.mm at 26 weeks and reached 1,000/40 c.mm at days 280. The rate of adult recovery was as high as 36%. Most worms were recovered from the heart and lungs (46%) and testes (40%). The male GN hamster-B. pahangi model could be a good substitution for the jird-B. pahangi model. Female GN and male APG hamsters seemed to be less susceptible than male GN hamsters. However, they could still be a better alternative to outbred hamsters due to their high rates of patency (92 and 100%), relatively high microfilarial densities (31 and 39/40 c.mm at 26 weeks) and reasonable rates of adult recovery (23.5 and 17.2%).en_US
dc.identifier.citationShigeno S, Yamashita S, Takahashi H, Kimura E, Aoki Y, Nakajima Y. Studies on Brugia pahangi in inbred hamsters. 1. Susceptibility of inbred GN and APG hamsters. The Southeast Asian Journal of Tropical Medicine and Public Health. 1983 Sep; 14(3): 407-12en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/32122
dc.language.isoengen_US
dc.source.urihttps://www.tm.mahidol.ac.th/seameo/publication.htmen_US
dc.subject.meshAnimalsen_US
dc.subject.meshBlood --parasitologyen_US
dc.subject.meshBrugiaen_US
dc.subject.meshCricetinae --parasitologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshFilariasis --parasitologyen_US
dc.subject.meshMaleen_US
dc.subject.meshMesocricetus --parasitologyen_US
dc.subject.meshMicrofilariaen_US
dc.subject.meshTime Factorsen_US
dc.titleStudies on Brugia pahangi in inbred hamsters. 1. Susceptibility of inbred GN and APG hamsters.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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