Association of anticardiolipin antibodies levels with instent restenosis in patients with coronary artery disease.
Loading...
Date
2008-07
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Present study was conducted to evaluate the association of IgG
anticardiolipin antibodies with instent restenosis in patients having
undergone percutaneous intervention with bare metal or drug eluting stents.
Coronary artery disease patients with stent placement at least 6 months
prior were screened for eligibility. 26 satisfied the inclusion/exclusion
criteria. 10 patients with symptoms of restenosis, confirmed on check
angiography served as cases and 16 without symptoms of restenosis served
as control. Unpaired t- test was applied to ascertain the significance of any
difference between control and study groups. Antibody levels were estimated
on ELISA reader. The mean (±SD) anticardiolipin antibodies levels in cases
and controls were 11.8±5.1 GPL/U/ml and 14.3±10.2 GPL/U/ml, respectively.
The difference was not statistically significant (P>0.05). In conclusion, we
did not observe any significant correlation between the level of IgG aCL
and instent restenosis.
Description
Keywords
instent restinosis, anticardiolepin antibody, coronary artery disease, patients
Citation
Sharma Sumali, Malhotra Anita, Sharma Y P, Pandhi P, Malhotra Samir, Nageswari K Sri, Shafiq Nusrat, Venkateshan S P, Kaur Ravnit. Association of anticardiolipin antibodies levels with instent restenosis in patients with coronary artery disease. Indian Journal of Physiology and Pharmacology. 2008 Jul-Sept; 52(3): 288-292.