Subacute Sclerosing Panencephalitis in a Tertiary Care Centre in Post Measles Vaccination Era.
| dc.contributor.author | Malik, Sonia | |
| dc.contributor.author | Dar, Lalit | |
| dc.contributor.author | Broor, Shobha | |
| dc.contributor.author | Gulati, Sheffali | |
| dc.contributor.author | Salhotra, Amandeep | |
| dc.contributor.author | Kalra, Veena | |
| dc.contributor.author | Behari, Madhuri | |
| dc.date.accessioned | 2013-09-17T10:09:18Z | |
| dc.date.available | 2013-09-17T10:09:18Z | |
| dc.date.issued | 2009-09 | |
| dc.description.abstract | This study was conducted to observe the impact of measles vaccination on the epidemiology of subacute sclerosing panencephalitis (SSPE) in the post measles vaccination era. This is a retrospective study from a tertiary care hospital, covering a ten year period starting a decade after the introduction of the national measles immunization programme in India. We analyzed 458 serologically confirmed SSPE cases. These patients had a high cerebrospinal fluid: serum anti-measles antibody ratio. The male to female ratio in the present study was 4.4:1. The mean age at onset of SSPE was 13.3 years, showing an increase in mean age at onset of SSPE. Clinical and other demographic details, available from 72 in-patients, are discussed in this report. Of these, a history of measles could be elicited in 34 cases. Mean latent period between measles infection and onset of SSPE was 7.8 years. Six patients gave a history of measles vaccination. A sizable percentage (15.5 %) of the patients was ≥ 18 years old and considered to have adult onset SSPE. The incidence of SSPE continues to be high and this report highlights the need for further strengthening routine measles immunization coverage. | en_US |
| dc.identifier.citation | Malik Sonia, Dar Lalit, Broor Shobha, Gulati Sheffali, Salhotra Amandeep, Kalra Veena, Behari Madhuri. Subacute Sclerosing Panencephalitis in a Tertiary Care Centre in Post Measles Vaccination Era. Journal of Communicable Diseases. 2009 Sept; 41(3): 161-167. | en_US |
| dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/148331 | |
| dc.language.iso | en | en_US |
| dc.source.uri | https://ismocd.org/jcd/41_3/3.pdf | en_US |
| dc.subject | SSPE | en_US |
| dc.subject | measles | en_US |
| dc.subject | serology | en_US |
| dc.subject | India | en_US |
| dc.title | Subacute Sclerosing Panencephalitis in a Tertiary Care Centre in Post Measles Vaccination Era. | en_US |
| dc.type | Article | en_US |