Effect of oral contraceptives on respiratory function.

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dc.contributor.authorResmi, S Sen_US
dc.contributor.authorSamuel, Elizabethen_US
dc.contributor.authorKesavachandran, Cen_US
dc.contributor.authorShashidhar, Shankaren_US
dc.date.accessioned2002-07-05en_US
dc.date.accessioned2009-06-01T05:12:08Z
dc.date.available2002-07-05en_US
dc.date.available2009-06-01T05:12:08Z
dc.date.issued2002-07-05en_US
dc.description.abstractThe present study was carried out to assess the lung functions in oral contraceptive administered women. Lung function tests were carried out with Spirometer (Vitallograph Compact II). A significant increase in vital capacity (VC) was observed in these women as compared to normal control. There was also a significant decrease in forced expiratory volume in 1 sec./vital capacity (FEV1/VC%) and forced expiratory volume in 1 sec./forced vital capacity (FEV1/FVC%) among oral contraceptive administered women as compared to controls. Further, a significant increase in peak expiratory flow rate (PEF), reduction in forced expiratory flow rate (FEF75-85%) and FEF75% were observed among oral contraceptive administered women as compared to controls. The increase in VC and PEF might be due to the synthetic form of progesterone (progestins) present in oral contraceptive pills which causes hyperventilatory changes. Synthetic progesterone during luteal phase of menstrual cycle might increase the static and dynamic volumes of lung i.e. VC and PEF. But FEF75% showed a decrease which might be due to the lower neuromuscular coordination during breathing.en_US
dc.description.affiliationSchool of Biosciences, Mahatma Gandhi University, Kottayam, 686 560.en_US
dc.identifier.citationResmi SS, Samuel E, Kesavachandran C, Shashidhar S. Effect of oral contraceptives on respiratory function. Indian Journal of Physiology and Pharmacology. 2002 Jul; 46(3): 361-6en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/106431
dc.language.isoengen_US
dc.source.urihttps://www.ijpp.comen_US
dc.subject.meshAdulten_US
dc.subject.meshBody Mass Indexen_US
dc.subject.meshContraceptives, Oral, Synthetic --adverse effectsen_US
dc.subject.meshEthinyl Estradiol --adverse effectsen_US
dc.subject.meshFemaleen_US
dc.subject.meshForced Expiratory Volume --drug effectsen_US
dc.subject.meshHumansen_US
dc.subject.meshNorgestrel --adverse effectsen_US
dc.subject.meshPeak Expiratory Flow Rate --drug effectsen_US
dc.subject.meshRespiratory Function Testsen_US
dc.subject.meshRespiratory Physiological Phenomena --drug effectsen_US
dc.subject.meshVital Capacity --drug effectsen_US
dc.titleEffect of oral contraceptives on respiratory function.en_US
dc.typeClinical Trialen_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
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