Transfusion related acute lung injury-TRALI: a review

Simple item page
dc.contributor.authorAlcazar-Castro, Javieren_US
dc.contributor.authorZarate-Aspiros, Alejandroen_US
dc.contributor.authorAndrade-Cuellar, Eliasen_US
dc.contributor.authorAlvarez-Perez, Brendaen_US
dc.contributor.authorValderrama-TreviƱo, Alan I.en_US
dc.contributor.authorRomero, Juan J. Granados-en_US
dc.contributor.authorBanegas-Ruiz, Rodrigoen_US
dc.contributor.authorBarrera-Mera, Baltazaren_US
dc.contributor.authorAlvarado-Rodriguez, Cristopheren_US
dc.contributor.authorUriarte-Ruiz, Karenen_US
dc.date.accessioned2020-11-18T09:58:24Z
dc.date.available2020-11-18T09:58:24Z
dc.date.issued2019-05
dc.description.abstractAcute pulmonary damage caused by transfusion is characterized by the sudden onset of respiratory distress in newly transfused patients within 6 hours after the transfusion, bilateral infiltrative changes in chest X-ray, PaO2/FIO2 <300 mmHg, absence of other risk factors for acute lung injury and absence of signs suggesting cardiogenic origin of pulmonary edema. Being one of the most serious complications of blood transfusion, plasma is the most involved factor, although all blood components can cause it, and is caused by antigen reactions/leukocyte antibody and lipid activity with ability to modify the biological response on primitive leukocytes. The diagnosis is based on the integration of clinical, radiological and gasometric elements, ruling out the rest of the possible causes of acute lung injury. Its differential diagnosis should include hemodynamic overload, anaphylactic reaction, bacterial contamination of transfused blood products and transfusion hemolytic reaction. The treatment is supportive measures based on the needs and does not differ from the treatment of acute lung injury secondary to other etiologies, severe cases require endotracheal intubation and mechanical ventilation while the non-severe can be managed with oxygen therapy.en_US
dc.identifier.affiliationsDepartment of Cardiac Electrophysiology Clinic and Arrhythmias, General Hospital of CDMX, MĆ©xicoen_US
dc.identifier.affiliationsAnesthesiology Service, General Hospital of CDMX, MĆ©xicoen_US
dc.identifier.affiliationsLaboratory of Experimental Immunotherapy and Tissue Engineering, Faculty of Medicine, UNAM, CDMX, MĆ©xicoen_US
dc.identifier.affiliationsDepartment of General Surgery, General Hospital of MĆ©xico, CDMX, MĆ©xicoen_US
dc.identifier.affiliationsService of Hand Surgery and Microsurgery, Rehabilitation Hospital, Luis Guillermo Ibarra Ibarra, CDMX, MĆ©xicoen_US
dc.identifier.affiliationsDepartment of Physiology, Faculty of Medicine, UNAM, CDMX, MĆ©xicoen_US
dc.identifier.affiliationsAFINES, School of Medicine, UNAM, Mexico City, Mexicoen_US
dc.identifier.citationAlcazar-Castro Javier, Zarate-Aspiros Alejandro, Andrade-Cuellar Elias, Alvarez-Perez Brenda, Valderrama-TreviƱo Alan I., Romero Juan J. Granados-, Banegas-Ruiz Rodrigo, Barrera-Mera Baltazar, Alvarado-Rodriguez Cristopher, Uriarte-Ruiz Karen. Transfusion related acute lung injury-TRALI: a review. International Journal of Research in Medical Sciences. 2019 May; 7(5): 1985-1991en_US
dc.identifier.issn2320-6071
dc.identifier.issn2320-6012
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/211316
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber5en_US
dc.relation.volume7en_US
dc.source.urihttps://dx.doi.org/10.18203/2320-6012.ijrms20191716en_US
dc.subjectBlood productsen_US
dc.subjectPulmonary injuryen_US
dc.subjectPlasmaen_US
dc.subjectRisk factoren_US
dc.subjectRespiratory insufficiencyen_US
dc.subjectTransfusionen_US
dc.titleTransfusion related acute lung injury-TRALI: a reviewen_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
ijrms2019v7n5p1985.pdf
Size:
342.76 KB
Format:
Adobe Portable Document Format
Download
Collections
International Journal of Research in Medical Sciences