Maternal and perinatal outcome in preterm premature rupture of membranes

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dc.contributor.authorR., Sudhaen_US
dc.contributor.authorBiradar, Priyankaen_US
dc.date.accessioned2024-09-24T09:01:15Z
dc.date.available2024-09-24T09:01:15Z
dc.date.issued2023-03
dc.description.abstractBackground: Preterm premature rupture of membranes (PPROM) and preterm birth results in one third of perinatal mortality and maternal morbidity such as chorioamnionitis and abruption placenta and preterm caesarean section, Preterm premature rupture of membranes occurs in 3% of pregnancies. PPROM is associated with intrauterine infection. Early detection of intrauterine infection may help in prevent neonatal sepsis. Objective of present study was to analyse the maternal and perinatal outcome of PPROM patients between 28 to 36 weeks +6 days and predict intrauterine infection by access the level of C reactive protein to prevent chorioamnionitis and neonatal infection.Methods: A descriptive study was conducted on 126 antenatal patients between 24 to 36 weeks+6 days with PPROM admitted to Department of Obstetrics and Gynaecology, Cheluvamba Hospital Mysore medical college, Mysore, Karnataka, India from February 2022 to July 2022. After establishing the diagnosis of PPROM patients were monitored and maternal and perinatal outcomes were studied.Results: 24% patients had late PPROM. 63% of early PPROM latency period >24 hours and were managed conservatively till 34 weeks. 18% had chorioamnionitis in that 12% CRP positive status and immediate termination of pregnancy. 73% of newborns in this group needed admission due to complications of prematurity like RDS (54.54%). Perinatal mortality (2.12%) was due to sepsis. 80% of late PPROM had latency period 24 hours and sepsis was 36% in >24 hours and 10% in <24 hours.Conclusions: The most common cause of perinatal mortality in early PPROM is prematurity and its complications. Hence conservative management to prolong pregnancy is recommended under strict monitoring for evidence of chorioamnionitis. C-reactive protein helps to pick up chorioamnionitis early. At the earliest evidence of chorioamnionitis termination irrespective of gestational age is warranted. In late PPROM, perinatal outcome is good. So, termination is advised as conservative management shall add to the fetal and maternal morbidity due to sepsis.en_US
dc.identifier.affiliationsDepartment of Obstetrics and Gynecology, Cheluvamba Hospital, Mysore Medical College Mysore, Karnataka, Indiaen_US
dc.identifier.affiliationsDepartment of Obstetrics and Gynecology, Cheluvamba Hospital, Mysore Medical College Mysore, Karnataka, Indiaen_US
dc.identifier.citationR. Sudha, Biradar Priyanka . Maternal and perinatal outcome in preterm premature rupture of membranes. International Journal of Reproduction, Contraception, Obstetrics and Gynecology . 2023 Mar; 12(3): 706-710en_US
dc.identifier.issn2320-1770
dc.identifier.issn2320-1789
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/231791
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber3en_US
dc.relation.volume12en_US
dc.source.urihttps://doi.org/10.18203/2320-1770.ijrcog20230542en_US
dc.subjectChorioamnionitisen_US
dc.subjectC-reactive proteinen_US
dc.subjectLatency perioden_US
dc.subjectMaternal outcomeen_US
dc.subjectPerinatal outcomeen_US
dc.subjectSepsisen_US
dc.titleMaternal and perinatal outcome in preterm premature rupture of membranesen_US
dc.typeJournal Articleen_US
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